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5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

AGA more common in men, increases with age, linked to family history, hypertension, dyslipidemia, and smoking.

Hair loss requires customized treatments based on its various causes and types.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

The document concludes that there is no clear definition of adequate health insurance, and a consistent method to measure underinsurance is needed.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Pregnant women's hair gets thicker.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

Pannexin 3 is important for bone formation and the development of bone cells.

Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Minoxidil helps prevent stress-caused hair loss in mice.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.