research Treatment of Hirsutism with the Pure Antiandrogen Flutamide
Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
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research Cepharanthine: An Update of Its Mode of Action, Pharmacological Properties, and Medical Applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Incidence of Liver Toxicity Associated with the Use of Flutamide in Prostate Cancer Patients
Flutamide rarely causes liver toxicity in prostate cancer patients.
research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Lowering testosterone speeds up wound healing in male mice.
research Oral Retinoids: Present Status
Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
research Keratin K15 as a Biomarker of Epidermal Stem Cells
Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
research Safety of Testosterone Treatment in Postmenopausal Women
Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
research Insulin Resistance and Skin Diseases
Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
research Keratinocyte Growth Inhibition Through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells
Androgens slow hair growth by altering Wnt signaling in balding cells.
research Peroxisome Proliferator-Activated Receptors (PPARs) and PPAR Agonists: The Future in Dermatology Therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Fadrozole And Finasteride Exposures Modulate Sex Steroid- And Thyroid Hormone-Related Gene Expression In Silurana (Xenopus) Tropicalis Early Larval Development
Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
research Multi-Layered Environmental Regulation on the Homeostasis of Stem Cells: The Saga of Hair Growth and Alopecia
Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells
Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma
WNT10A helps esophageal cancer cells spread and keep renewing themselves.
research Botulinum Toxin Off-Label Use in Dermatology: A Review
Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
research Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract
Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
research Gender Aspects in Skin Diseases
Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.
research Idiopathic Hirsutism: Androgen Role and Treatment Options
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research Is Seborrhea a Sign of Autonomic Impairment in Parkinson's Disease?
Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
research Endocrine-Skin Interactions
Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.
research Endocrine Care of Transpeople Part I: A Review of Cross-Sex Hormonal Treatments, Outcomes, and Adverse Effects in Transmen
Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
research Genome-Wide Meta-Analysis Implicates Mediators of Hair Follicle Development and Morphogenesis in Risk for Severe Acne
Genetic variations affecting skin structure play a key role in severe acne.
research Evidence-Based Approach to Cutaneous Hyperandrogenism in Women
The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
research Hutchinson-Gilford Progeria Syndrome: Current Status and Prospects for Gene Therapy Treatment
Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
research Topical Melatonin for Treatment of Androgenetic Alopecia
Melatonin solution helps treat hair loss in men and women.
research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study
Apple extract called procyanidin B-2 was found to greatly increase hair growth.
research Testosterone Therapy in Women: Myths and Misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.