January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
36 citations,
July 1980 in “Journal of Toxicology and Environmental Health” High doses of ethynylestradiol in rats caused growth issues, organ changes, and some tumors, but didn't increase overall tumor rates.
25 citations,
May 2013 in “Journal of mammary gland biology and neoplasia” Hedgehog signaling is crucial for mammary gland development over hair follicles.
22 citations,
August 1999 in “Mechanisms of Development” Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.
25 citations,
September 1977 in “Journal of Toxicology and Environmental Health” High doses of some contraceptive steroids cause health issues in dogs, but their relevance to humans is unclear.
November 2018 in “Atlas of genetics and cytogenetics in oncology and haematology” WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” SLICK cattle have better heat tolerance due to specific gene expression and pathway differences.
1 citations,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keeping β-catenin levels high in mammary cells disrupts their development and branching.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
1 citations,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
1 citations,
January 1998 in “International journal of cancer” Rubbing vitamin D3 on skin can help prevent hair loss from chemotherapy and slow breast tumor growth in mice.
12 citations,
February 2011 in “Equine veterinary education” A mare had severe symptoms and died from a large lymphoma.
February 2017 in “Developmental Cell” Mammary stem cells drive mammary gland growth by branching and cell mixing.
19 citations,
January 2015 in “Development” Hoxc8 gene helps start mammary gland development by controlling specific signals.
8 citations,
November 2013 in “PLOS ONE” Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.
721 citations,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
218 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
86 citations,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
October 2017 in “Chinese Journal of Dermatology” 43 citations,
October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
February 2021 in “Facta Universitatis” Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.
April 2016 in “Chinese Journal of Dermatology” Wnt10b can help regenerate hair follicles.
July 2014 in “Plastic and Reconstructive Surgery” Sentinel lymph node biopsy is recommended for all types of desmoplastic melanoma due to higher rates of nodal metastasis.
July 2014 in “Plastic and Reconstructive Surgery” The rib-sparing technique in breast reconstruction may lead to more complications without reducing the need for further surgery.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
July 2014 in “Plastic and Reconstructive Surgery” Hair follicles stored in a special medium had the highest survival rate, and "plucked" follicles and follicular units showed better growth after transplant.
July 2014 in “Plastic and Reconstructive Surgery” Hair follicles stored in a special medium and certain types of grafts have higher survival and growth rates after transplantation.
July 2014 in “Plastic and Reconstructive Surgery” The document concludes that rib-sparing techniques in breast reconstruction have limited benefits, sentinel lymph node biopsy is needed for desmoplastic melanoma, certain hair preservation methods improve graft survival, partial turbinectomy effectively reduces nasal obstruction, nipple shields with irrigation may reduce capsular contracture, and thicker malignant melanomas have a higher risk of non-skin cancers.
2 citations,
December 2020 in “Developmental cell” Chemotherapy drugs can cause abnormal growth and changes in healthy skin and gland cells.
January 2015 in “Elsevier eBooks” CA VI helps maintain pH balance and is important for various bodily functions.