TLDR Wnt10b can help regenerate hair follicles.
The document from April 15, 2016, discussed the role of Wnt10b, a highly conserved secretory glycoprotein, in the cyclical regeneration of hair follicles. The researchers found that overexpression of Wnt10b, mediated by adenovirus, could induce cyclical regeneration of hair follicles, possibly through the classical Wnt signaling pathway. This study aimed to provide a deeper understanding of the expression characteristics of hair follicles induced by Wnt10b, elucidate its mechanism of action in the hair follicle cycle, and provide a theoretical basis for the development of drugs to treat hair follicle cycle-related diseases.
10 citations,
May 2021 in “Clinical, cosmetic and investigational dermatology” UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.
7 citations,
January 2019 in “PeerJ” A protein called sFRP4 can slow down hair regrowth.
14 citations,
July 2017 in “Fitoterapia” Oleanolic acid promotes hair growth by increasing cell proliferation through the Wnt/β-catenin pathway.
9 citations,
January 2016 in “International Journal of Medical Sciences” Increasing Wnt10b levels can help grow new hair follicles in mice.
1 citations,
January 2015 in “Genetics and Molecular Research” Stopping S100A3 activity slows down hair growth in mice.
53 citations,
April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
5 citations,
January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
27 citations,
May 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b is important for starting hair growth and developing hair follicles.