January 2023 in “Archives of Disease in Childhood Education & Practice” This article describes the causes of hirsutism, introduces a novel assessment tool, and suggests strategies for investigation and management, but provides no new experimental results.
This study synthesizes current evidence showing that menopause involves a predictable endocrine transition, while male ageing features a more variable testosterone decline, necessitating a nuanced clinical approach to diagnosis and treatment.
October 2024 in “Irish Journal of Medical Science (1971 -)” Continuous glucose monitoring and GLP-1 receptor agonists improve diabetes management, but personalized care and education are crucial.
April 2020 in “Journal of the Endocrine Society” This case report emphasizes the importance of recognizing non-classic congenital adrenal hyperplasia as a cause of hyperandrogenism and the need for genetic counseling given potential familial implications.
January 2009 in “Side effects of drugs annual” This study observed no teratogenic effects of oral decongestants and surprisingly favorable neonatal outcomes in Swedish women who used them during pregnancy.
June 1995 in “International Journal of Gynecology & Obstetrics” This article provides citations without reporting new findings on androgen conjugate levels in alopecia.
March 2026 in “Nutrients” This study found that adequate vitamin D status is necessary for metformin to effectively reduce prolactin levels in men with iatrogenic hyperprolactinemia, while improvements in glycemic control were observed across all vitamin D groups.
6 citations
,
October 2024 in “Reviews in Endocrine and Metabolic Disorders” In this review, researchers found that while hyper- and hypoprolactinemia in PCOS patients are linked to metabolic changes, intermediate prolactin levels might be protective, but more robust prospective studies and clinical trials are needed to confirm these findings and develop treatments.
12 citations
,
September 1999 in “The journal of experimental zoology/Journal of experimental zoology” This study found that reducing circulating PRL levels is not necessary for the onset of winter hair growth in mink and that adrenal glands do not inhibit this process through DHEA or its metabolite Delta(5)-DIOL.
3 citations
,
June 2024 in “International Journal of Molecular Sciences” In this review, the potential role of the hormone prolactin in skin biology and its implications for treating skin diseases and hair disorders are explored, with a focus on its stress-related impacts and possible immunomodulatory function in the context of COVID-19.
33 citations
,
January 2002 This study found that daily topical application of 500 microg/ml latanoprost led to moderate to marked hair regrowth in a macaque model of androgenetic alopecia.
7 citations
,
October 2019 in “Case reports in endocrinology” This case report describes a woman with hyperandrogenism and menstrual disturbances, where an ovarian steroid cell tumor was identified and removed, leading to resolution of symptoms.
October 2010 in “Reproductive Biomedicine Online” Women with pituitary adenomas often have reproductive issues, like irregular periods and trouble getting pregnant, but not always breast milk production without pregnancy.
25 citations
,
June 2004 in “Journal of Investigative Dermatology” This study found that macrophage-stimulating protein (MSP) enhanced hair growth in both human hair follicles cultured in vitro and in mice through the promotion of anagen phase induction.
37 citations
,
March 2010 in “British Journal of Dermatology” Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.
2 citations
,
January 1989 in “PubMed” In this study, 48% of women with androgenetic alopecia showed hypothyroidism or hyperprolactinemia after TRH stimulation, suggesting these conditions may influence androgen metabolism and contribute to hair loss.
18 citations
,
November 1998 in “Comparative biochemistry and physiology. Part A, Molecular & integrative physiology” This study found that serum prolactin and dehydroepiandrosterone levels did not determine the onset of mink hair growth cycles, though their metabolites may influence other aspects of hair growth.
2 citations
,
March 2023 in “Experimental neurology” In this study, pregnenolone was found to dose-dependently reduce L-DOPA-induced dyskinesias in a rat model of Parkinson's disease, suggesting its potential as a therapeutic target for these dyskinesias.
This study found that men with early-onset androgenic alopecia may be partially resistant to the cardiometabolic benefits of bromocriptine compared to those with normal hair growth.
1 citations
,
October 2022 in “International journal of endocrinology” This study found that dihydrotestosterone treatment in female rats altered anterior pituitary gland gene expression, with significant repression of prolactin and inhibition of GnRH receptor gene expression, suggesting specific hormone production changes.
May 1981 in “Inpharma (Balgowlah)” Medroxyprogesterone acetate improved sleep apnea symptoms in some obese patients.
36 citations
,
July 2005 in “Journal of Neuroendocrinology” This study suggests that both the central biosynthesis and metabolism of progesterone to 3α,5α‐THP in the ventral tegmental area are crucial for facilitating lordosis in female rats.
1 citations
,
January 2021 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This report suggests a potential link between hyperprolactinemia and alopecia in women with autoimmune thyroid disease and emphasizes the importance of considering other causes in diagnosis.
29 citations
,
October 2009 in “Pharmacology Biochemistry and Behavior” January 2010 in “Acta Universitatis Medicinalis Nanjing” This study found that progesterone increased the survival of newborn neurons and enhanced spatial learning and memory in adult male mice, independent of neuron production changes.
October 2022 in “The Journal of Clinical Pharmacology” This study found that men with early-onset androgenic alopecia are less responsive to the cardiometabolic effects of bromocriptine compared to men with normal hair growth.
October 2024 in “Journal of Medical and Scientific Research” This study found that serum prolactin levels were significantly higher in patients with psoriasis, alopecia areata, and vitiligo compared to healthy controls, and prolactin levels were also correlated with disease severity in psoriasis and alopecia areata patients.
October 2013 in “International Journal of Pediatric Endocrinology/International journal of pediatric endocrinology” This case report describes a boy with hypothalamic hamartoma experiencing pubertas precox and gelastic seizures, where leuprorelin therapy's effect on pubertas precox was controversial, but valproic acid effectively managed gelastic seizures.
6 citations
,
September 2010 in “Animal” This study found that selecting Angus cattle for early puberty reduced their prolactin levels, which may indicate a response to changing day length.
103 citations
,
April 2005 in “Experimental dermatology” This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.