14 citations
,
March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that serum MIF levels were significantly higher in patients with extensive alopecia areata compared to those with mild alopecia areata and healthy individuals.
3 citations
,
October 1994 in “Medical Molecular Morphology” This study observed that the lower part of vibrissa hair roots in adult Wistar rats receives a richer blood supply and structural protection, compared to the upper part.
88 citations
,
April 1981 in “Molecular and cellular biochemistry”
182 citations
,
June 2017 in “Biomaterials” This study found that adipose-derived mesenchymal stem cells produced more anti-inflammatory and pro-angiogenic cytokines on electrospun scaffolds, which enhanced wound healing and macrophage activity in a rat model.
April 2026 in “Experimental & Molecular Medicine” This study used integrated single-cell chromatin and transcriptomic analyses in developing mouse skin to uncover gene networks involved in skin lineage specification and identified Mef2c+ upper fibroblasts as potential precursors to certain muscle-like structures, with cross-species findings in human skin.
5 citations
,
April 2019 in “Journal of The American Academy of Dermatology” This review discusses the complex nature of frontal fibrosing alopecia, suggesting it is a misnomer and possibly a subset of lichen planopilaris, but reports no new clinical results.
1 citations
,
May 2024 in “Dermatology and Therapy” This review article examines the current understanding of frontal fibrosing alopecia, noting its prevalence in different demographics and the roles of genetic and environmental factors in its pathogenesis, while highlighting that treatment approaches remain varied and lack standardization.
30 citations
,
October 1994 in “Journal of Cutaneous Pathology” This article describes a case of multiple perifollicular fibromas and suggests that cases previously reported as such might actually be instances of Birt‐Hogg‐Dubé syndrome.
July 2023 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, researchers analyzed skin tumors from patients with CYLD cutaneous syndrome and found that loss of CYLD function is linked to changes in cellular signaling pathways, particularly NF-κB signaling, and leads to increased secretion of specific extracellular matrix proteins.
62 citations
,
March 2015 in “PLOS ONE” In this study, microporous electrospun scaffolds pre-seeded with dermal fibroblasts accelerated wound healing and improved dermal matrix structure and hair follicle regeneration compared to acellular scaffolds in a rat model.
175 citations
,
December 2014 in “PLoS Biology” This study found that macrophages near hair follicles contribute to the activation of skin epithelial stem cells in mice, suggesting a novel role for macrophages in regulating hair growth.
27 citations
,
February 2003 in “Cell and Tissue Research” This study found that FM dyes are effective markers for tracing live Merkel cells in in vitro experiments, as they remain visible for at least seven days and highlight cell shape better than quinacrine.
39 citations
,
July 2015 in “British Journal of Dermatology” This article discusses the pseudo 'fringe sign' in frontal fibrosing alopecia, highlighting that it is not solely related to traction, and it reports no new clinical results.
April 2018 in “Journal of Investigative Dermatology” This study found that desmosomal cadherin desmoglein 3 loses its rigidity upon Ca2+ removal, regardless of desmosome functional state, suggesting a central role for signaling in hyper-adhesion.
23 citations
,
January 2017 in “Current Rheumatology Reports” This study found that adipocytes in the interfacial white adipose tissue adjacent to fibrotic lesions in systemic sclerosis show unique phenotypes and contribute to the condition's pathogenesis.
36 citations
,
July 1988 in “Archives of Dermatological Research” Pili annulati is caused by a protein metabolism disorder affecting hair structure.
10 citations
,
January 2010 in “International journal of trichology” This study found that keratin-associated proteins form part of the developing exocuticle and a-layer in hair fiber cuticle cells, while cornified envelope proteins were absent.
December 2025 in “Doğu Fen Bilimleri Dergisi” In this study, researchers found that the expression of vimentin, desmin, and laminin in rat skin contributes to cell structure and tissue integrity, with varying reactions across different cell types.
1 citations
,
December 2018 in “Journal of cutaneous pathology” This study found that 11% of cutaneous focal mucinosis lesions demonstrated follicular induction, which can mimic basal cell carcinoma histologically and complicate diagnosis.
6 citations
,
January 2017 in “British Journal of Dermatology” This article reviews frontal fibrosing alopecia, exploring its characteristics, demographics, and associated conditions, and calls for controlled trials due to an increase in worldwide cases; it reports no new findings.
23 citations
,
January 1981 This article reviews the composition and structure of mammalian hard keratins, focusing on the filamentous and nonfilamentous protein content, and reports no new experimental results.
16 citations
,
February 2010 in “Journal of the European Academy of Dermatology and Venereology” This article is a letter to the editor about fibrosing alopecia in a pattern distribution and reports no new research findings.
119 citations
,
November 2014 in “Trends in Cell Biology” This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.
1 citations
,
September 2021 in “CRC Press eBooks” This chapter reviews trichoscopic-pathologic correlations in Frontal Fibrosing Alopecia and reports no new clinical results; the authors discuss genetics, clinical patterns, and unusual variants associated with this condition.
August 2015 in “Dermatología Argentina” This study reviewed 18 postmenopausal women with frontal fibrosing alopecia, noting frontotemporal hairline recession and eyebrow loss, often treated with steroids, triamcinolone, and other medications.
April 2023 in “Journal of Investigative Dermatology” In this study, researchers discovered that fat grafting helps reduce dermal fibrosis in radiation-injured mouse skin by decreasing specific fibroblast subpopulations associated with Fra/c-Jun signaling.
January 2025 in “Nature Communications” Using synchrotron X-ray imaging, this study mapped the complex innervation of male rat vibrissa follicles, revealing distinct types of myelinated afferent neurons and patterns of axonal organization that may inform sensory processing in the brainstem.
1 citations
,
February 2017 in “The American journal of dermatopathology/American journal of dermatopathology” This case report presented a 52-year-old man with cutaneous focal mucinosis, exhibiting rare follicular induction of the epidermis, underscoring the importance of recognizing this association in differential diagnoses.
This study found that fibroblasts from Emery-Dreifuss muscular dystrophy patients with certain genetic mutations overexpress markers of fibrosis, and gene correction techniques reduced fibrogenic molecule expression in cell models, suggesting potential therapeutic applications.
46 citations
,
December 2001 in “Journal of Endocrinology/Journal of endocrinology” This study found that mouse FLRG protein, a secreted glycoprotein, is expressed in certain tissues and plays a role distinct from follistatin during wound healing, suggesting different functions in vivo.