Multiple Perifollicular Fibromas: Report of a Case and Literature Analysis

The document described a case of a patient with multiple perifollicular fibromas and analyzed existing literature on the condition. Perifollicular fibroma was identified as a cutaneous hamartomatous proliferation of the pilar connective tissue sheath, characterized histologically by collagen fibers surrounding an unaltered hair follicle. Clinically, these fibromas were typically multiple and appeared on the face and upper trunk. The presentation was similar to that seen in Birt-Hogg-Dubé syndrome, which also includes fibrofolliculomas, trichodiscomas, and acrochordons. The study suggested that some earlier reports of multiple perifollicular fibromas might have been unrecognized cases of Birt-Hogg-Dubé syndrome.