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    Did you mean Perifollicular Fibrosis?
    GlossaryPerifollicular Fibrosis

    formation of scar tissue around hair follicles

    Perifollicular fibrosis is a condition where scar tissue forms around hair follicles, leading to their gradual destruction. This scarring can impede hair growth and is often associated with certain types of hair loss, such as cicatricial alopecia.

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      research Multiple perifollicular fibromas: report of a case and analysis of the literature

      30 citations , October 1994 in “Journal of Cutaneous Pathology”
      The document described a case of a patient with multiple perifollicular fibromas and analyzed existing literature on the condition. Perifollicular fibroma was identified as a cutaneous hamartomatous proliferation involving the pilar connective tissue sheath, with a histological appearance of concentric collagen fibers around an unaltered hair follicle. Clinically, these fibromas were typically multiple and located on the face and upper trunk. The presentation was similar to Birt‐Hogg‐Dubé syndrome, which also included fibrofolliculomas, trichodiscomas, and acrochordons. The document suggested that earlier reports of multiple perifollicular fibromas might have been unrecognized cases of Birt‐Hogg‐Dubé syndrome.

      research Giant Rhinophyma

      September 2020 in “Advances in anatomic pathology”
      A woman's large nose growth was initially misdiagnosed, but later confirmed to be giant rhinophyma after full removal and examination.

      research A Pedunculated Follicular Hamartoma: A Case Showing a Central Trichofolliculoma‐like Tumor with Multiple Trichogenic Tumors

      4 citations , August 1991 in “The Journal of Dermatology”
      The document reported a rare case of a pedunculated follicular hamartoma on the nasal septum of a 77-year-old Japanese male. The nodule measured 11x11x10 mm and was skin-to-pink colored. Histopathological examination revealed a well-formed dilated hair follicle at the tumor's central pore, containing keratin debris and vellus hairs. Epithelial cells proliferated from the central follicle to the peripheral epidermis, forming long thin strands or immature follicle-like structures. A primary germinal bud with thick concentric collagen fibers and sparse elastic fibers was a distinctive feature. Although the tumor showed characteristics of a trichofolliculoma with desmoplasia, trichogenic trichoblastomas, and perifollicular fibromas, it was more accurately described as a pedunculated follicular hamartoma due to its pathological and clinical features.

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