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research Role of Dermal Factors Involved in Regulating the Melanin and Melanogenesis of Mammalian Melanocytes in Normal and Abnormal Skin
Dermal factors are crucial in regulating melanin production in skin.
![COVID-19 and Hypopituitarism](/images/research/b4249819-b772-4d94-bdb0-57d2864a6dd8/small/13197.jpg)
research COVID-19 and Hypopituitarism
COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
![Folliculitis Decalvans: A Review of Current Treatment Modalities](/images/research/69d92822-dfcf-4b74-b65c-1043f91201ce/small/36339.jpg)
research Folliculitis Decalvans: A Review of Current Treatment Modalities
Current treatments for folliculitis decalvans include antibiotics, isotretinoin, and potential new therapies like botulinum toxin A and PRP.
research Antigen Presenting Cells in the Skin of a Patient with Hair Loss and Systemic Lupus Erythematosus
Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
![Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance](/images/research/bab31691-f4e4-43f0-8b30-650663ba82d2/small/16731.jpg)
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
![Wnt Is Back in Drugmakers' Sights, but Is It Druggable?](/images/research/61e1e377-e1b1-4eab-baf2-7d378be8de4d/small/22623.jpg)
research Wnt Is Back in Drugmakers' Sights, but Is It Druggable?
Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
![Identification of Two Distinct Stem Cell Clusters, Lrig1-Derived and Wnt/CD44-Dependent, in Corneal Epithelium](/images/research/3e37fcb2-413a-44db-80c7-e6099651aa5e/small/17945.jpg)
research Identification of Two Distinct Stem Cell Clusters, Lrig1-Derived and Wnt/CD44-Dependent, in Corneal Epithelium
The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
![PPAR-γ Modulation as a Novel Therapeutic Strategy for Scarring Alopecia](/images/research/02ac35f5-b949-4b9e-ac82-4819f9e2fa60/small/17950.jpg)
research PPAR-γ Modulation as a Novel Therapeutic Strategy for Scarring Alopecia
A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
![Decoding Frontal Fibrosing Alopecia and Lichen Planopilaris: Macrophages Hold the Key?](/images/research/3abd8929-e04a-46ce-bcc6-2afa7d3deede/small/17938.jpg)
research Decoding Frontal Fibrosing Alopecia and Lichen Planopilaris: Macrophages Hold the Key?
Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
research A Folliculocentric Perspective of Dandruff Pathogenesis: Could a Troublesome Condition Be Caused by Changes to a Natural Secretory Mechanism?
Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
![Essential Thrombocythemia: The Dermatologic Point of View](/images/research/f3817b50-9b2d-4707-a98a-91f67cdfb59f/small/31623.jpg)
research Essential Thrombocythemia: The Dermatologic Point of View
Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.
![Practical Approaches to Medical and Cosmetic Dermatology in Skin of Color Patients](/images/research/e7b85b15-992a-4faf-ba67-546f3208398c/small/27804.jpg)
research Practical Approaches to Medical and Cosmetic Dermatology in Skin of Color Patients
The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.
![Clinical Case Notes: Intraorbital Ophthalmic Artery Aneurysms](/images/research/25cc392c-f321-4070-b859-1ad5ea4025d7/small/15301.jpg)
research Clinical Case Notes: Intraorbital Ophthalmic Artery Aneurysms
Eye exams are crucial for kids with 13q deletion syndrome, tamoxifen can cause vision loss, Propecia may lead to cataracts, Lipoid Proteinosis causes skin bumps, and OCT is useful for diagnosing macular diseases.
![Clinical Case Notes: Retinoblastoma, Microphthalmia, and Chromosome 13q Deletion Syndrome](/images/research/80987b43-19a4-4ba8-9bf8-4b76db725329/small/15299.jpg)
research Clinical Case Notes: Retinoblastoma, Microphthalmia, and Chromosome 13q Deletion Syndrome
The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.
![Clinical Case Notes: Propecia-Associated Bilateral Cataract](/images/research/fa2f035a-9777-49d8-8bd3-97abf7f03bbc/small/15302.jpg)
research Clinical Case Notes: Propecia-Associated Bilateral Cataract
Taking Propecia might lead to the development of cataracts.
![Clinical Case Notes: Optical Coherence Tomography of Adult-Onset Foveomacular Vitelliform Dystrophy](/images/research/61a446f1-115c-43d1-b9e5-b5b0b05490b1/small/15314.jpg)
research Clinical Case Notes: Optical Coherence Tomography of Adult-Onset Foveomacular Vitelliform Dystrophy
Multiple eye conditions were studied, highlighting the importance of various imaging methods for diagnosis, the vision side effects of drugs tamoxifen and Propecia, and the usefulness of optical coherence tomography for diagnosing and monitoring macular and retinal diseases.
![Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors](/images/research/ae33eed6-7eb3-4924-a132-553d2ea87c31/small/14627.jpg)
research Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors
Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
![Rabson-Mendenhall Syndrome: Two Case Reports and a Brief Review of the Literature](/images/research/7ecab2a7-e0e1-4a6e-8b19-94221c40a22b/small/14897.jpg)
research Rabson-Mendenhall Syndrome: Two Case Reports and a Brief Review of the Literature
The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.
![Genetic Susceptibility to Alopecia](/images/research/65212008-75aa-4bbb-9f3b-fe1cb8a94934/small/17744.jpg)
research Genetic Susceptibility to Alopecia
Certain mutations in the PADI3 gene may increase the risk of developing a type of scarring hair loss common in women of African descent.
![Lichenoid Red Tattoo Reaction and Alopecia Areata](/images/research/176df18a-7dc4-451b-bdf6-2a6cb48767f4/small/21924.jpg)
research Lichenoid Red Tattoo Reaction and Alopecia Areata
A man's red tattoo caused a skin reaction and hair loss in his beard, which improved after treatment.
![A Case of Folliculitis Decalvans With Concomitant Acne Keloidalis Nuchae, Androgenic Alopecia, and Profound Postinflammatory Hyperpigmentation](/images/research/f50279eb-75ea-4ef6-b06f-881754cfe417/small/4522.jpg)
research A Case of Folliculitis Decalvans With Concomitant Acne Keloidalis Nuchae, Androgenic Alopecia, and Profound Postinflammatory Hyperpigmentation
A 37-year-old man with hair loss and skin issues was successfully treated with oral antibiotics, highlighting the need for early treatment. Long-term care includes low-dose antibiotics and avoiding caps and wigs.
![Clinicopathologic Case 2: Multiple Intraoral White Lesions in a 55-Year-Old Female](/images/research/f137c499-9699-4209-a305-26c8524b65c2/small/38288.jpg)
research Clinicopathologic Case 2: Multiple Intraoral White Lesions in a 55-Year-Old Female
The patient was diagnosed with oral lichen sclerosus and needs long-term monitoring.
![The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells](/images/research/1e23ee09-7f8b-476d-9937-7986628b97cc/small/18593.jpg)
research The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
![Type-2 Immunity Associated With Type-1 Related Skin Inflammatory Diseases: Friend Or Foe?](/images/research/e970c856-058b-4ae8-9dbe-388e6e230663/small/41327.jpg)
research Type-2 Immunity Associated With Type-1 Related Skin Inflammatory Diseases: Friend Or Foe?
Type-2 immunity may influence skin diseases and could be targeted for treatment.
![The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside](/images/research/ae023163-52f0-4aa6-a6ae-bb3a052be231/small/34716.jpg)
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
![Recent Progress in Understanding the Effect of Sympathetic Nerves on Hair Follicle Growth](/images/research/e9ca47fc-4582-476a-af79-50d39ba23917/small/17150.jpg)
research Recent Progress in Understanding the Effect of Sympathetic Nerves on Hair Follicle Growth
Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.
![Ophiasis Alopecia Areata Treated with Microneedling](/images/research/e0acad62-bb18-46cb-9267-aab5fe90ab3c/small/4808.jpg)
research Ophiasis Alopecia Areata Treated with Microneedling
Microneedling with triamcinolone helps hair regrowth in ophiasis alopecia areata.
![A Study to Evaluate the Efficacy of Various Topical Treatment Modalities for Alopecia Areata](/images/research/322537b0-b3e6-44ff-86c5-25f7f0510570/small/32466.jpg)
research A Study to Evaluate the Efficacy of Various Topical Treatment Modalities for Alopecia Areata
Steroids are the best treatment for Alopecia Areata with few side effects.