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Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Married Egyptian women with PCOS have lower sexual desire compared to those without PCOS.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Some breast cancer chemotherapy can cause permanent hair loss.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain drugs that block specific enzymes can help treat prostate diseases.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.