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LSD1 is crucial for regenerating hair cells in zebrafish.

This study found that in mice, LSD1 interacting with HSP90 accelerates skin wound healing by enhancing HFSC glycolytic metabolism, proliferation, and differentiation via the c-MYC/LDHA axis.

This study found that LSD1 is crucial for embryonic skin barrier formation in mice, revealing its significant role in epidermal development and suggesting its potential as a target in skin diseases with barrier defects.

This study reported that in a mouse tail wound model, the synthetic dual inhibitor corin accelerated wound closure by enhancing re-epithelialization, and further in vitro experiments demonstrated increased expression of genes promoting keratinocyte migration, suggesting its potential as a treatment for chronic wounds.

This study suggests that recombinant Lumpy Skin Disease Virus strains pose a severe threat to yaks in the Qinghai-Tibet Plateau, causing high mortality and emphasizing the need for targeted control strategies.

This study suggests that vitamin D deficiency is likely not involved in the development of frontal fibrosing alopecia, as patients showed similar vitamin D levels to those with female pattern hair loss.

This study suggests that flibanserin may have a similar safety profile in men to that observed in premenopausal women, with positive responses reported for various sexual dysfunctions, but further research is needed.

This study describes a case series of nine patients experiencing symptoms of selenium toxicity after consuming a liquid dietary supplement with an excess amount of selenium.

This study suggests that dietary grape powder may reduce the severity of atopic dermatitis in a mouse model, highlighting its potential in both prevention and intervention settings.

This study found that bioelectric and biochemical signaling mechanisms coordinate collective cell movement during chicken feather bud morphogenesis, suggesting a potential new angle for research in skin development and wound healing.

This study suggests that hormone replacement therapy and oral contraception may have a protective role in scarring alopecia, as these were reported less frequently by patients with the condition compared to those with female pattern hair loss.

In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

This study found that induced expression of mir-302 can reprogram human hair follicle cells into induced pluripotent stem cells through a novel epigenetic mechanism involving global demethylation.

This study identified five potential molecular targets for future androgenetic alopecia therapy using genome-wide gene-expression investigations and bioinformatics analyses.

In this study, low-level laser therapy significantly improved the mechanical strength of bone at tooth extraction sites in rats, while neither platelet-rich plasma alone nor combined with laser affected mechanical strength or calcium content.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

This study developed a testosterone propionate-induced C57BL/6 mouse model of androgenetic alopecia, demonstrating that high-dose, prolonged testosterone administration inhibited hair regrowth and mirrored human AGA pathology, providing a useful platform for studying hair loss mechanisms and testing therapies targeting the Wnt/β-catenin pathway.

In this study, applying a 5% concentration of pomegranate peel extract significantly enhanced hair growth on male rabbits, showing results comparable to the positive control using 2% Minoxidil, but higher concentrations or lower concentrations did not perform as well.

This study examined the effects of purified Albizia saponaria bark extract on hair growth in rabbits, finding that a 20% concentration of the extract increased hair weight significantly, though it was less effective than minoxidil.

This study on UVB-exposed mice found that topical application of 10% Rosmarinus officinalis essential oil significantly increased hair length and follicle diameter, attributed potentially to its antioxidant compounds.

In a conditional knockout mouse model, this study found that loss of the transcription elongation factor SPT6 in basal keratinocytes led to psoriasis-like skin inflammation and delayed wound healing, suggesting SPT6 plays a crucial role in maintaining epidermal immune quiescence by suppressing proinflammatory NF-κB signaling.

This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.

In this study, the authors observed that testosterone therapy shortened the QTc interval and normalized T-wave morphology in men with acquired LQTS or TdP linked to hypogonadism, suggesting testosterone may be helpful in treatment.

This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.

This review discusses the biochemical and biological functions of histone demethylases and their potential involvement in human diseases, including cancer, but reports no new findings.

This study suggests that phenotypic plasticity, including processes like dedifferentiation and transdifferentiation, plays a crucial role in cancer initiation, progression, and therapy resistance, broadening our understanding of cancer dynamics and potential treatment strategies.

This review discusses the role of jumonji family proteins in chromatin regulation and development, highlighting their involvement in transcriptional repression and histone demethylation, but reports no new experimental findings.

This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.

This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.