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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The Rotterdam Study aims to understand various diseases in older adults.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Some medicinal plants can help heal wounds and may lead to new treatments.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

CDP is crucial for lung and hair follicle cell development.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Platelet-rich plasma (PRP) is a cheap and easy treatment for hair loss, but not suitable for everyone. It also helps in healing ulcers, rejuvenating skin, and improving hair transplants.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.