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The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Some treatments can help with hair regrowth in alopecia areata, but results vary and long-term use is often needed without changing the disease's outcome.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

PRP therapy increases hair density for androgenetic alopecia.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

Children and adults with Cushing's disease show different symptoms and males have more severe cases; surgery outcomes can be predicted by certain factors.

PCOS is a common hormonal disorder in women, often involving menstrual issues and increased diabetes risk, managed through lifestyle changes and targeted treatments.

Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Finasteride doesn't harm bone density in older men with BPH.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.

Both emollients effectively reduced itching and improved skin moisture in xerotic eczema.

Long pulsed Nd: YAG laser is safe and effective for long-term hair reduction in darker skin types.

Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

Finasteride slightly better long-term, minoxidil faster initial results, but stopping minoxidil may cause hair loss.

Treating hidradenitis suppurativa needs long-term care and teamwork among doctors, but there's a lack of strong guidance on how to do it.

High levels of cortisol in hair show long-term stress which can lower fertility in animals.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.