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The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

Inositol was not more effective than a placebo in treating trichotillomania.

Spironolactone most effective for hirsutism, but has side effects.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Hirsutism is often caused by high male hormone levels and can be treated with lifestyle changes and medications.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Stopping fluoride toothpaste use might improve perioral dermatitis.

Testosterone is crucial for development, growth, and various body functions in mammals.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.