July 2022 in “BMJ Case Reports” Early treatment is crucial to prevent severe eye complications from caterpillar hair.
January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
Early NAS level changes affect alcohol consumption vulnerability.
July 2013 in “British Journal of Dermatology” The document reviews key historical figures and discoveries in dermatology.
June 2008 in “Dermatologic Surgery” Hydrogen peroxide may have both positive and negative effects on wound healing, and its safe concentration for hair transplant surgery is unclear.
April 2003 in “Experimental Dermatology” The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
January 1989 in “Journal of The American Academy of Dermatology” Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
November 2020 in “Journal of The American Academy of Dermatology” The conclusion is that many small genetic variations influence claw disorders in cows, and using genomic selection could help reduce these disorders.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
61 citations,
April 2018 in “Frontiers in endocrinology” Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.
50 citations,
February 2013 in “BMC evolutionary biology” Cetaceans lost hair due to changes in the Hr and FGF5 genes.
16 citations,
January 2021 in “Frontiers in veterinary science” Pigs in farrowing crates and loose-housing systems showed no difference in chronic stress levels as measured by hair cortisol.
8 citations,
January 2023 in “International journal of molecular sciences” Transglutaminase activity is important for skin and is found in both mammals and birds.
7 citations,
January 2019 in “Journal of clinical medicine research” Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
3 citations,
February 2015 in “Mechanisms of development” Hormones and stretching both needed for nipple area skin growth in mice.
3 citations,
September 2014 in “SpringerPlus” Human hair loss may have evolved to help increase brain size.
December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
107 citations,
June 1997 in “PubMed” EGFR is essential for normal hair development and follicle differentiation.
83 citations,
August 2018 in “BJOG” Uterine transplants for transgender women are feasible but need more research.
73 citations,
December 2015 in “Nature Genetics” Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
45 citations,
April 2009 in “Journal of anatomy” Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.
42 citations,
September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
35 citations,
March 2010 in “BMC veterinary research” Goats with BSE or scrapie show varying symptoms, and using only clinical signs may not detect all scrapie cases.
34 citations,
February 2015 in “Frontiers in Cellular Neuroscience” The study used zebrafish to investigate drug-induced hair cell death and identify protective agents. Zebrafish were ideal due to their genetic similarities to mammals and external hair cells. Researchers found three zebrafish mutants resistant to neomycin-induced hair cell death, involving genes not previously linked to hair cell toxicity. They screened 10,960 compounds, identifying several protective agents, including FDA-approved drugs. The study revealed that many protective compounds did not affect the bactericidal activity of aminoglycosides, except Benzamil. Selective estrogen receptor modulators were effective against neomycin exposure. The research highlighted disrupted calcium homeostasis as a mechanism of hair cell toxicity, with calcium release from the endoplasmic reticulum causing mitochondrial dysfunction and increased reactive oxygen species. The zebrafish model was effective in understanding hair cell death mechanisms and identifying potential treatments for hearing loss and balance disorders.
22 citations,
May 2019 in “Animals” High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.
18 citations,
February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
15 citations,
July 2021 in “Bosnian Journal of Basic Medical Sciences” Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.