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Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Bioprinting could improve wound healing but needs more development to match real skin.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

PEVs improve minoxidil skin penetration, increasing hair growth.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.