research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
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research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted 99mTc-Radioimaging Agents
Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
research Multicentric Parallel Phase II Trial of the Polo-Like Kinase 1 Inhibitor BI 2536 in Patients With Advanced Head and Neck Cancer, Breast Cancer, Ovarian Cancer, Soft Tissue Sarcoma, and Melanoma. The First Protocol of the European Organization for Research and Treatment of Cancer Network of Core Institutes
BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
research Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial
Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.
research The Role of Macrophages in Skin Homeostasis
Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
research Review Article: Dermatological Complications of Immunosuppressive and Anti-TNF Therapy in Inflammatory Bowel Disease
Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
research Resolution of Paraneoplastic Alopecia Following Surgical Removal of a Pancreatic Carcinoma in a Cat
Removing a cat's pancreatic cancer can temporarily reverse hair loss caused by the disease.
research Baldness, Acne, and Testicular Germ Cell Tumors
Men with testicular cancer were less likely to experience baldness and severe acne.
research Treatment of Female Pattern Hair Loss with the Androgen Receptor Antagonist Flutamide
Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.
research Anti-Androgen Effects of Extracts and Compounds from Ganoderma Lucidum
Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research All-Cause and Cause-Specific Mortality Risks Associated With Alopecia Areata
People with alopecia areata have similar overall death rates as others but higher risks of death from self-harm, psychiatric issues, and lung cancer in certain cases.
research Cardiovascular Effects of Hormone Therapy for Prostate Cancer
Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.
research Rash from EGFR Inhibitors: Opportunities and Challenges for Palliation
EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma
The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
research Dermatologic Reactions to Targeted Therapy
Targeted cancer therapies can cause skin side effects, which should be treated early to help patients' quality of life and treatment adherence.
research Role of 5 Alpha-Reductase Inhibitors in the Management of Prostate Cancer
5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Development of Prostate Cancer in a Patient with Primary Hypogonadism: Intratumoral Steroidogenesis in Prostate Cancer Tissues
Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
research Open-Label, Randomized, Multicenter, Phase III Study Comparing Oral Paclitaxel Plus Encequidar Versus Intravenous Paclitaxel in Patients With Metastatic Breast Cancer
Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.
research Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme
Certain Dibenzo derivatives may help treat prostate cancer.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Feline Paraneoplastic Alopecia Associated with Metastasizing Intestinal Carcinoma
A cat with hair loss and illness was found to have cancer spread from its colon.
research Origanum Vulgare L. Leaf Extract Alleviates Finasteride-Induced Oxidative Stress in Mouse Liver and Kidney
Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.
research Expression of Plectin-1 and Trichohyalin in Human Tongue Cancer Cells
Tongue cancer cells show more plectin-1 than non-cancer cells, but both have similar levels of trichohyalin.
research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
research Dermatologic Care of the Transplant Patient
Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.
research Assessment of the Effect of Ficus Carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3, and Caspase-9 in Inducing Intrinsic Apoptosis Cascade
Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.