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Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Finasteride helps reduce heart issues and improves heart function.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Finasteride can cause sexual problems and depression in young men.

The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

3D cell-derived matrices improve tissue regeneration and disease modeling.

Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

Testosterone helps human pancreatic cells increase insulin release.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.