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Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Neurosteroids show promise for treating epilepsy and more research is needed.

Orbital decompression surgery for Graves' orbitopathy caused double vision in 19% of patients, with similar rates for two surgical methods.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Folliculitis is an inflammation of hair follicles that requires proper diagnosis and treatment based on the specific cause.

Some patients taking antipsychotic medications experience skin reactions, ranging from mild to severe.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

Minoxidil use increases facial hair growth in females, more in older users.

Notch-related genes play a key role in the development and cycling of hair follicles.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.

Ginseng, especially red ginseng, helps hair grow by increasing blood flow and energy to hair roots.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Most patients treated with low-dose alpha-interferon for malignant melanoma experienced skin side effects, with hair loss being the most frequent.

New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Jaw wiring helps with weight loss but long-term habits are needed to keep it off.

Patients with PCOS rate their hirsutism higher than clinicians, and these self-ratings are more closely related to their quality of life and risk of depression.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.