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Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

Resveratrol-loaded nanoparticles show promise for lung cancer treatment.

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

TLR2, a component in hair follicle stem cells, is crucial for healthy hair growth and regeneration, and its decrease can lead to hair loss.

New treatments for sudden hair loss include oral medications and a special laser, both showing promise in hair regrowth.

Follicle Stimulating Hormone is important for fertility.

Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

Vitamin D is important for skin cell growth and health, and its active form and receptor play key roles in skin and hair processes.

Bexarotene 1% topical gel helped some patients with alopecia areata regrow hair.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Regenerated hairs can regain their color if the wound occurs during a certain stage of hair growth, and this process is helped by specific skin cells and proteins.

Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.

Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Fat tissue stem cells may help increase hair growth.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Blocking a specific receptor slows down hair loss in mice.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.