Search
for
Sort by
Research
150-180 / 1000+ resultsresearch Dutasteride: a review of current data on a novel dual inhibitor of 5alpha reductase.
This study found that dutasteride effectively improves symptoms of benign prostatic hyperplasia, showing benefits in urinary flow and quality of life, with only modestly elevated sexual side effects compared to placebo.
research Serenoa repens (saw palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
This review concludes that the global literature supports the efficacy and safety of lipidosterolic extract of Serenoa repens in treating lower urinary tract symptoms, comparable to alpha-blockers and 5α-reductase inhibitors.
research 5α-reductase inhibitors/finasteride
This study demonstrated that 12 months of 5 mg daily finasteride treatment reduced prostate volume, dihydrotestosterone, and prostate-specific antigen levels, while improving urinary flow rates and symptom scores in benign prostatic hyperplasia patients.
research Comparative Study of Therapeutic Effect of Dibenyline, Finasteride, and Combination Drugs for Symptomatic Benign Prostatic Hyperplasia
This study found that combining dibenyline and finasteride for symptomatic BPH treatment offered modest improvements with fewer additional side effects compared to each drug alone.
research Risks Associated with 5α-Reductase Inhibitor Use: Analysis of Adverse Drug Reactions Reported to EudraVigilance
This study found that while 5α-reductase inhibitors like finasteride had many serious, unresolved adverse drug reactions, some were not listed in the existing product information.
research Re: Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials
This review discusses the impact of 5α-reductase inhibitors on sexual function and presents results from a meta-analysis of randomized controlled trials, without reporting new clinical findings.
research Health Canada has approved finasteride [Proscar; Merck Frosst] and doxazosin cotherapy
research 290 Efficacy of Low-Intensity Shock Wave Therapy for the Treatment of ED in Diabetic Patients : A Pooled Analysis
Low-intensity shock wave therapy is effective in treating erectile dysfunction in diabetic patients.
research Finasteride
research Determination of finasteride in human plasma and its pharmacokinetics and relative bioavailability by HPLC-electrospray mass spectrometry
This study found that two formulations of finasteride tablets are bioequivalent in healthy male volunteers, with similar pharmacokinetic profiles.
research Does the use of finasteride lead to sexual dysfunction?
This study found that patients using finasteride were up to twice as likely to experience sexual dysfunction, including ejaculation disorder, decreased libido, and impotence, compared to those not using the drug.
research MAASALONG Reviews 2022 UPDATE
This article is a promotional piece about the MaasaLong supplement, which is claimed to improve male health concerns like erectile dysfunction, with no new empirical research results reported.
research Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis
This study found that 5α-reductase inhibitors significantly increase the risk of erectile dysfunction and hypoactive sexual desire in men with benign prostatic hyperplasia, compared to placebo.
research Focus sulla finasteride: efficacia, meccanismi e raccomandazioni per l'uso clinico
This analysis concluded that finasteride effectively reduces prostate size and urinary symptoms in benign prostatic hyperplasia, offering a favorable safety profile and versatility as a treatment option.
research Three months extended-release microspheres prepared by multi-microchannel microfluidics in beagle dog models
This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.
research Pharmacokinetics and Bioequivalence of Finasteride Tablets in Healthy Subjects
This study determined that finasteride test and reference tablets are bioequivalent in human participants, as no significant differences were found in their pharmacokinetic parameters.
research Bioequivalence Study of Finasteride Tablets in Healthy Volunteers
In this study, the authors concluded that the tested and reference finasteride tablets showed bioequivalence in healthy male volunteers.
research Inhibition of steroid 5 alpha-reductase with finasteride: sleep-related erections, potency, and libido in healthy men
research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.
research Determination of Finasteride in Human Plasma by LC-MS and Study on its Bioequivalent
In this study, the researchers found that two formulations of finasteride tablets were bioequivalent in Chinese healthy male volunteers.
research Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS)
This study identified distinct and significant adverse event patterns across different drug classes used to treat benign prostatic hyperplasia, confirming known risks and suggesting novel safety signals for further investigation.
research Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry
This study developed a novel method to simultaneously measure finasteride, dutasteride, and related biomarkers in serum, finding that both drugs lowered DHT levels while increasing substrate concentrations.
research Інгібітор 5α-редуктази дутастерид при лікуванні доброякісної гіперплазії передміхурової залози: системний огляд та мета-аналіз
This systematic review evaluated the efficacy and safety of dutasteride in men with benign prostatic hyperplasia and found that dutasteride significantly reduced the need for prostate surgery and acute urinary retention episodes compared to finasteride, with no significant difference in safety profiles between the two.
research Inhibitory Effect of Extract of Urtical Mairei Levl on 5α-Reductase Activity
This study found that the n-butanol extract from Untica mairei Levl's roots significantly inhibited 5α-reductase activity in an in vitro model using rat prostate enzyme.
research P0401 Finasteride 1 mg: Silent impacts on male fertility despite preserved hormonal balance
research Disfunción eréctil : función endotelial e interacción hormonal, efectos sobre la salud vascular -De la fisiopatología molecular a los aspectos clínicos-
This study found a significant correlation between estradiol/testosterone imbalance and erectile dysfunction severity in Klinefelter syndrome patients, also highlighting high satisfaction with penile prosthesis in both psychogenic and organic cases.
research 전립선비대증의 치료로 Tamsulosin, Finasteride 병합요법시 투여 방법 및 증상호전에 따른 약물 순응도의 차이 분석
This study concluded that packaging tamsulosin and finasteride together for co-administration in patients with benign prostatic hyperplasia improves medication adherence compared to packaging each drug separately.
research Finasterida: Diez Años De Uso Clínico. Revisión Sistemática De La Literatura
This review found strong evidence supporting Finasteride's effectiveness in reducing symptoms and improving quality of life in patients with larger prostate volumes, earning it a grade A recommendation for clinical use.
research Sexual side effects of 5-α-reductase inhibitors finasteride and dutasteride: A comprehensive review
This review discusses the sexual side effects of finasteride and dutasteride, two 5-α-reductase inhibitors, and reports no new clinical findings while calling for further research into dosage differences.