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The research suggests new treatments for skin cancer could target specific cell growth pathways.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Lymphatic vessels are important for skin repair and could affect skin disease treatments.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

Two young cats with a severe ear and skin condition improved with immune system-targeting treatments.

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.