Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified 14 different phytoconstituents in the methanolic fruit extract of Citrullus colocynthis, suggesting its potential pharmacological importance.

This study found that a food supplement containing L-cystine, pantothenic acid, biotin, and millet extract significantly improved hair density and beauty parameters in healthy Japanese women with light diffuse hair loss after three months.

In this study, researchers found that supplementation with L-cystine, either alone or with a keratin hydrolysate, significantly improved hair density, hair and nail brightness, and nail growth in women experiencing acute telogen effluvium and brittle nail syndrome over three months.

This review discusses mechanisms and potential dietary influences on alopecia, proposing molecular targets like TRPVs and endocannabinoids as avenues for treatment but reports no new clinical results.

This study assessed the effects of a formulation containing millet extract, wheat germ oil, L-cystine, and calcium pantothenate on women with telogen effluvium using Digital Phototrichogram, but it reports no new results.

This article examines the PCPT study on whether daily finasteride can reduce prostate cancer incidence, describing its methodology and findings but reporting no new clinical results.

This article reviews treatments for androgenic alopecia, discussing options like minoxidil for both genders and specific therapies for men and women, but it reports no new clinical results.

This study suggests that increased Wnt signaling may promote excessive differentiation of melanocytes, leading to exhaustion of melanocyte stem cells and hair graying in aged mice.

This study concluded that a combination of millet seed extract, L-cystine, and calcium pantothenate may improve anagen hair rate in women with androgenetic alopecia over six months.

This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.

This study found that mice deficient in the enzyme cathepsin L exhibited impaired degradation of autophagolysosomal content, leading to an accumulation of large, abnormal vesicles in various tissues.

This study found that cystatin M/E strongly inhibits human cathepsin V and cathepsin L via distinct non-overlapping sites, suggesting an important role in human epidermal differentiation and hair follicle morphogenesis.

Cathepsin L deficiency causes hair and skin issues in mice.

This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.

Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.

This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.

This research found that hyaluronic acid increased cell proliferation and type I collagen more effectively than poly-L-lactic acid in both human fibroblast cultures and rat dermis.

Combination therapy improves urinary flow and reduces residual urine, but needs better stent design.

This review compiles existing research on Peperomia pellucida's traditional medicinal uses and pharmacological properties but reports no new findings, suggesting its potential for drug development.

This study found that mice genetically modified to overexpress the serine protease inhibitor hurpin showed reduced UV-induced apoptosis but increased susceptibility to skin cancer after chemical carcinogenesis.

This research found that a biodegradable fibrous membrane incorporating fibroblast-derived ECM accelerated wound healing and improved neovascularization in a mouse model.

This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.

In this study, researchers tested lotions containing DGLA, S-equol, and propionyl-l-carnitine on individuals with androgenic alopecia, noting a significant increase in hair count for women and a marginal increase for men after 6 months, along with improved hair cycle dynamics.

In this study, autophagy was commonly observed during keratinization in neonate rat hair follicles, suggesting lysosomal proteases and cytoplasmic enzymes may coordinate in hair follicle cell differentiation.

This study identified a new heterozygous missense variant in CST6 associated with autosomal dominant keratosis follicularis spinulosa decalvans in an Austrian family, affecting epidermal differentiation and hair formation.

In this study, the lack of cathepsin expression in Kaposi's sarcoma lesions suggests a benign hyperplastic origin for these lesions.

PLLA injections can cause hair loss and skin issues.

This study found that a 2.5% flavonoid-rich extract of Equisetum hyemale promoted hair growth in a rat model of chemically-induced alopecia, showing results comparable to 5% minoxidil.

This article discusses the limitations of relying on literature and regulatory documents for pharmaceutical evidence, proposing public health decisions be based on independent trials like those by the Mario Negri Institute.