Hair Regenerative Activities of Flavonoid-Rich Extract of Equisetum Hyemale in Chemically-Induced Alopecia in Sprague Dawley Rats
January 2019
in “
Journal of pharmacy & pharmacognosy research
”
flavonoid-rich extract Equisetum hyemale chemically-induced alopecia Sprague Dawley rats ethyl acetate extract depilated areas dorsal skin hair growth minoxidil tensile strength follicular growth telogen phase flavonoid extract horsetail extract alopecia rats ethyl acetate hair loss skin hair regeneration Rogaine hair strength hair follicles resting phase
TLDR The flavonoid-rich extract of Equisetum hyemale can help regrow hair in cases of alopecia.
The study evaluated the hair-regenerative properties of a flavonoid-rich ethyl acetate extract from Equisetum hyemale in Sprague Dawley rats with chemically-induced alopecia. Various concentrations of the extract were applied to depilated areas on the rats' dorsal skin, and hair growth was monitored over 28 days. The 2.5% extract showed significant hair-regenerative effects, comparable to 5% minoxidil, with high tensile strength, combined masses, and follicular growth, particularly in the telogen phase. The findings suggested that the 2.5% flavonoid-rich extract of E. hyemale could effectively promote hair regeneration in situ.
