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Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

Estrogens and progesterone are key in regulating melasma pigmentation.

Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Global oil use will rise, US corn-to-ethanol policy is flawed, and various social and economic issues need attention.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Understanding where cancer cells come from helps create better prevention and treatment methods.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Skin-derived precursors in hair follicles come from different origins but function similarly.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.