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This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.

In this study, researchers identified two distinct homozygous mutations in the KRT85 gene among consanguineous Pakistani families with pure hair and nail ectodermal dysplasia, highlighting variations in severity and potential impacts on the K85 protein function.

This study found that overexpressing FGF22 in dermal papilla cells enhanced hair follicle stem cell proliferation and viability, while its knockout reduced these attributes, indicating its role in hair follicle regeneration.

This study found that while most mice lacking MK6a and MK6b genes died from tongue epithelium disintegration, about 25% survived and showed no hair or nail defects due to a newly discovered MK6hf gene.

This study concluded that the inner root sheath inhibits the expression of certain differentiation markers in hair bulbs, with calcium-induced changes paralleling those seen in hair follicle mid-segments.

This case report documents the first use of bimekizumab as monotherapy for dissecting cellulitis of the scalp, where a 27-year-old man experienced significant symptom relief without adverse effects after failing standard treatments.

This article reviews the genetic foundations of keratins in maintaining epithelial tissue integrity and links specific keratin variants to diverse ichthyosis forms, without presenting new clinical findings.

In this case report, researchers identified a potential adverse skin reaction, called SDRIFE or Baboon syndrome, caused by the drug tofacitinib in a 19-year-old woman being treated for alopecia subtotalis, leading the authors to recommend discontinuation of the drug.

In this study, researchers developed and evaluated a hair serum using Murraya koenigii and Clitoria ternatea extracts, finding that the F3 formulation had strong antifungal activity and was effective in dandruff management, suggesting potential benefits for scalp health.

This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.

This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.

WIF1 helps keep skin stem cells inactive to prevent excessive cell growth.

This study found that keloid patients exhibited significantly higher expression levels of NEDD4-TV3 and IGF-1 genes compared to controls, indicating a potential role of these genes in predicting and understanding keloid formation.

This study suggests that the PI3K-AKT signaling pathway may significantly influence the development of different hair types in Inner Mongolia cashmere goats.

This study found that trichohyalin is expressed in various normal and pathological epithelia beyond hair follicle cells, where it is uniquely associated with filaggrin, suggesting a specific role in aggregating K6/K16-containing intermediate filaments.

This study highlights the successful design of recombinant fortilin constructs for potential drug development targeting atherosclerotic plaque formation in cardiovascular disease.

This study found that SCUBE3 protein is upregulated in various cancers, promoting tumor growth and poor outcomes, while suppressing growth in renal cell carcinoma, and may serve as a diagnostic marker and potential therapeutic target for several diseases due to its secreted nature.

This study identified a new genetic variant in the KRT71 gene responsible for a breed-specific form of hypotrichosis in Hereford cattle, potentially serving as a model for similar human conditions.

Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.

This study found that the creation of hair follicle lumens in mice is driven by the outward migration of keratin 79-positive cells, suggesting a novel mechanism for generating hollow cores in hair follicles.

This study found that vesicles formed with behenyltrimethylammonium chloride, stearic acid, and hinokitiol significantly improved skin permeation of hinokitiol in vitro, which may aid in hair growth promotion.

This study reports for the first time on the expression patterns of Id2 and Id3 proteins in developing hair follicles, suggesting a significant role for these proteins in hair follicle development and epithelial-mesenchymal interactions.

This article reviews keratosis follicularis squamosa, a keratinizing disorder predominantly found in the Japanese population, but reports no new clinical results.

This study found that straight crimp mutant wool differs from crimpy wool in the layout of cortical cells and the relative proportions of keratin and keratin-associated proteins.

This study found that Krox20 marks a diverse stem cell population in mouse hair follicles, which significantly contributes to the interfollicular epidermis and regulates epidermal homeostasis.

This review discusses recurrent implantation failure (RIF) in IVF, noting the lack of standard definitions or treatment protocols, and emphasizes the need for individualized treatment and further research.

This study proposes a new method to selectively isolate keratin-associated proteins and keratin from human hair, suggesting that KAPs may support keratin fibers in hair structure.

In this study, researchers developed de novo designed hetero-bifunctional proteins as an alternative approach for targeted protein degradation, successfully targeting BCL-xL for degradation in cells and inducing apoptosis, which may expand the range of addressable E3 ligases and disease targets.

This study identified a novel KRT86 mutation associated with autosomal dominant monilethrix, expanding understanding of its genetic basis beyond known motifs.