Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this case report, a 7-year-old girl developed a painless, slowly growing keratinous cyst at her umbilicus, which was successfully resected and identified as a benign skin lesion; the authors emphasized the importance for clinicians to consider this diagnosis in pediatric umbilical tumors.

This study describes two new types of dermal keratinous cysts of the eyelids, derived from the pilosebaceous apparatus, each presenting distinct management challenges.

This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.

This case report describes a proliferating trichilemmal cyst that underwent malignant transformation, with specific keratins identified in the tumor but no epidermal keratin detected.

This study suggests that eruptive vellus hair cysts often have atypical pathological changes and likely originate from the infrainfundibulum and sebaceous duct based on keratin expression analysis.

This article discusses the characteristics, clinical presentation, and diagnosis of calcified epidermal cysts but reports no new clinical results.

This article reviews the composition and structure of mammalian hard keratins, focusing on the filamentous and nonfilamentous protein content, and reports no new experimental results.

This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.

This review discusses the evolutionary history of keratins and reports no new results, highlighting key events that contributed to the development of mammalian hair and integument.

This article discusses eruptive vellus hair cysts, detailing their appearance, distribution, histology, and potential spontaneous resolution, but reports no new clinical findings on treatment.

This study found that keratins have evolutionarily conserved and domain-selectively enriched amino acids, which likely reflect their unique structural roles, with distinct patterns observed among epidermal, hair, and simple-type epithelial keratins.

Hair and follicle keratins differ in structure and expression, especially in cysteine content.

This study found that, compared to oxidative treatments, reductive perm-waving more severely impacts the intermediate filaments in European human hair, while both treatments alter denaturation kinetics in a first-order manner.

This study observed that exposing human hair keratins to heat or UV treatments led to modifications in cysteine residues, disrupting crucial disulphide bonds and potentially reducing the structural integrity of hair similar to prolonged styling or sunlight exposure.

This study found that trichostasis spinulosa was present in some seborrheic keratoses, indicating they may partly originate from hair follicle cells.

This case study highlights congenital atrichia with papular lesions as a cause of total body hair loss, characterized by the absence of hair follicles and the presence of skin-colored papules.

This case report describes a 45-year-old woman with a trichoadenoma of the eyelid, emphasizing the importance of histopathological examination for accurately diagnosing excised eyelid lesions.

In this study, the authors emphasize the importance of accurately diagnosing congenital atrichia with papules—a condition marked by hair loss and papular skin lesions—differentiating it from other similar disorders to prevent unnecessary treatments and inform families about its benign but irreversible nature.

In this case study, a 51-year-old Japanese man was diagnosed with desmoplastic trichoepithelioma after histological examination of surgically excised facial plaques.

This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.

In this study, researchers mapped cysteine accessibility in wool keratins and KAPs, revealing that certain cysteines in keratin end domains and Types I and II rod domains are accessible and likely involved in forming disulfide bonds.

This study provides insight into the specific disulfide bond interactions between keratins and keratin associated proteins, suggesting non-random cysteine interactions crucial for stabilizing hair fiber structure.

This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.

This study demonstrated that human hair keratins have strong antioxidative properties, providing protection against oxidative stress in human dermal fibroblasts, suggesting their potential as antioxidizing supplements.

This study found that a laboratory model using nude mice can produce human hair follicles with amino acid compositions resembling both normal and trichothiodystrophy-affected human scalp hair over extended periods.

This study found that depleting HIF-P4H-2 in FoxD1-lineage cells in mice led to disrupted hair follicle development, resulting in truncal alopecia but normal cranial hair, suggesting its crucial role in hair homeostasis.

Hair is culturally and economically valuable, and its weight is now used to measure the effectiveness of hair growth treatments.

This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.

This study identified a new 65 kD and 48 kD keratin pair expressed in specific mouse epithelial sites, suggesting a unique evolutionary branch of hair-related keratins.

This study observed that mercury-lamp irradiation may cause cleavage of disulfide bonds in keratins of white hair, leading to the formation of thiols in laboratory settings.