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The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Using neurohormones to control keratin can lead to new skin disease treatments.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Keratin mutations cause skin diseases and could lead to new treatments.

The man has a genetic skin condition called pachyonychia congenita.

Neurohormones help control skin health and could treat skin disorders.

K16 can partially replace K14 but causes hair loss and skin issues.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

The most common cause of hair loss in children is tinea capitis, followed by alopecia areata and telogen effluvium.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.

The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.

The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.

Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.

New genetic discoveries may lead to better treatments for alopecia areata.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.