11 citations
,
January 2014 in “Open journal of veterinary medicine” In these clinical cases, topical propolis treatment effectively resolved canine dermatophytosis, including hair regrowth, with no known side effects, suggesting it as a promising natural treatment option.
15 citations
,
May 2011 in “Veterinary Dermatology” In this study, dogs with sebaceous adenitis were treated with oral vitamin A, but responses varied widely, showing improvements in some cases while others experienced no benefit.
39 citations
,
November 1984 in “Journal of Cardiovascular Pharmacology” Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
22 citations
,
January 2020 in “Veterinary dermatology” This review discusses the unique characteristics and taxonomy of Malassezia yeasts and examines current diagnostic and therapeutic approaches in veterinary medicine; it reports no new clinical findings.
January 2025 in “LUMEN ET VIRTUS” In this study, a case of alopecia X in a male, uncastrated German Spitz dog was successfully managed with orchiectomy and melatonin, leading to partial hair regrowth and improved dermatological condition after 90 days of treatment.
January 2013 in “Juui rinshou hifuka” A Toy Poodle with hair loss regrew hair after being treated with melatonin and finasteride.
5 citations
,
January 2021 in “Veterinary dermatology” This study found that adding low-level laser therapy to conventional treatment for canine acral lick dermatitis significantly increased hair growth compared to conventional therapy alone, but did not significantly reduce licking behavior.
1 citations
,
March 2017 in “Semina Ciências Agrárias” This case report describes a Dogo Argentino dog with M. nanum infection, likely from hunting wild boar, that responded well to itraconazole and topical miconazole treatment.
January 2014 in “INTAS POLIVET” This case study reports successful healing and hair regrowth from skin grafting in a Labrador retriever with an extensive forelimb injury, observing complete epithelial covering by day 25 and hair growth by day 60 post-operation.
March 2026 in “Buletin Veteriner Udayana” In this study, dogs with atopic dermatitis showed significant improvements in macroscopic skin lesions, such as reduced pruritus and hair regrowth, after receiving coconut oil massages every three days for 33 days.
1 citations
,
January 2021 in “Advances in animal and veterinary sciences” This study observed a high prevalence of the dermatophyte M. canis in humans and pets in Egypt, particularly highlighting the potential for zoonotic transmission from dogs and cats to humans.
426 citations
,
August 2014 in “Nature Medicine” This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.
415 citations
,
January 2008 in “Cell” NFATc1 controls hair stem cell activity, affecting hair growth and could be a target for hair loss treatments.
272 citations
,
September 2001 in “Journal of Biological Chemistry” This study cataloged human type II hair keratins, detailing their expression and differentiation roles in hair follicles and comparing them with type I keratins to explore keratin-pairing principles.
249 citations
,
November 2018 in “Cell” TNFα helps grow and maintain liver cells in 3D culture for a long time.
235 citations
,
July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” This study establishes a catalog of human type I hair keratins and identifies their specific roles and expression patterns during hair differentiation and growth in scalp follicles.
224 citations
,
February 2013 in “The Journal of clinical investigation/The journal of clinical investigation” This study identifies SOX9 as a critical downstream effector of ERG in TMPRSS2:ERG fusion-positive prostate cancer, indicating its role in tumor invasion and growth.
166 citations
,
November 2008 in “Expert Review of Endocrinology & Metabolism” This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.
103 citations
,
April 2010 in “Journal of Investigative Dermatology” This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.
93 citations
,
July 2006 in “Journal of Investigative Dermatology” This study describes the expression patterns of type I inner root sheath keratin proteins K25–K28 in human hair follicles, highlighting their distinct distribution within different layers.
79 citations
,
August 1998 in “The Journal of Cell Biology” In a transgenic mouse model, this study found that overexpression of keratin 16 in skin keratinocytes led to hyperkeratosis and increased EGF receptor signaling, altering skin cell behavior and structure.
77 citations
,
March 2000 in “Journal of Investigative Dermatology” The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.
77 citations
,
June 2002 in “Journal of Investigative Dermatology” CD44 variant changes start alopecia areata, but don't maintain it.
76 citations
,
January 2022 in “Journal of Tissue Engineering” This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.
62 citations
,
December 2007 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that enzymatic conversion of Arg-51 in S100A3 protein to citrulline promotes homotetramer assembly, potentially increasing Ca²⁺ binding required for hair cuticular barrier formation.
48 citations
,
May 2021 in “Molecules” The researchers found that plant extracts from Papaver rhoeas L., Clitoria ternatea L., and Carthamus tinctorius L. are effective natural cosmetic dyes, offering intense and stable colors without cytotoxicity.
44 citations
,
January 2004 in “American journal of clinical dermatology” This review covers various disorders of cornification and their treatments, offering clinical insights but reporting no new research findings.
42 citations
,
January 2014 in “BMC Genomics” This study highlights the loss of hair-type keratin genes in cetaceans compared to terrestrial mammals, suggesting a potential adaptive role linked to their hairless phenotype and habitat changes.
40 citations
,
September 2010 in “Journal of Biological Chemistry” This study found that keratin K80, structurally similar to hair keratins, is broadly expressed in various epithelial tissues and is involved in intermediate filament formation with multiple type I partners.
38 citations
,
November 2020 in “International journal of biochemistry & cell biology” This review discusses the biological roles and diagnostic significance of keratins in mammalian colon epithelial cells and reports no new clinical results.