March 2025 in “International Journal of Molecular Sciences” This study established a Krt24-CreERT2 mouse line targeting outer bulge hair follicle stem cells, finding these cells crucial for hair follicle development and repair, particularly following ionizing radiation exposure.
May 2010 in “Europe PMC (PubMed Central)” This chapter discusses the synthesis and analysis of near-infrared fluorescent activity-based probes for imaging cysteine protease activity, reporting potential benefits for disease diagnosis but noting challenges in imaging specific locations with high cathepsin activity.
26 citations
,
July 2007 in “Biochemical Pharmacology” This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.
4 citations
,
September 2021 in “Medical Lasers” This review reports that low-level laser therapy may effectively prevent and alleviate oral mucositis from chemotherapy, supporting its use as a viable treatment option.
3 citations
,
June 2025 in “Stem Cell Research & Therapy” Hair follicle-derived melanocyte transplant could effectively treat vitiligo by restoring skin color.
4 citations
,
February 2019 in “Revista da Associação Médica Brasileira” This study found that FOLFOX6 chemotherapy significantly decreased serum VEGF and CRP levels in advanced colorectal cancer patients, improved their quality of life as measured by KPS scores, and demonstrated a high overall therapeutic efficacy of 82.72% with manageable side effects.
2 citations
,
February 2025 in “Advanced Healthcare Materials” This study developed microfluidics-based 3D microtumors to model minimal residual disease in ovarian cancer, highlighting their alignment with patient-derived MRD and response to a fatty acid oxidation inhibitor.
3 citations
,
September 2001 in “Dermatologic Surgery” This study found that adding a 5 W CO2 laser to an Er:YAG laser improved hemostasis without significantly affecting mean hair counts or increasing lateral thermal damage in men with androgenetic alopecia.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduces the N-K Healing Series, an alternative geometric approach to medicine, claimed to restore tissue fully and eliminate pain without the traditional drawbacks, allegedly achieving results beyond mainstream medical treatments in simulated injury scenarios.
6 citations
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March 2022 in “IET Image Processing” This study utilized ultrasound biomicroscopy to evaluate the anterior chamber in angle closure glaucoma patients, revealing that the anterior chamber angle is wider on the downside than the upside and identifying important parameters for potential laser surgery.
April 2026 in “Biosensors” In this study, red-light irradiation significantly increased hair follicle numbers and ATP levels in a mouse model, highlighting low-level laser therapy's potential to enhance hair regeneration and alter the skin metabolic microenvironment.
18 citations
,
August 2009 in “Skin Research and Technology” In this study, optical coherence tomography was used to produce 3D images of human hair, revealing that after chemical treatment with ammonium thioglycolate, the main hair structures were not identifiable due to damage.
September 2015 in “Photodiagnosis and Photodynamic Therapy”
73 citations
,
October 2003 in “Journal of Pharmacology and Experimental Therapeutics” This study found that hair depigmentation in mice and humans can be a dynamic indicator of KIT inhibition by the drug SU11248, correlating with treatment periods.
1 citations
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January 2012 in “InTech eBooks” In this study, higher doses of daunorubicin during induction therapy significantly improved complete remission rates in young adults with acute myeloid leukemia.
21 citations
,
January 2007 in “Journal of Drugs in Dermatology” This study found that the 3-msec alexandrite laser effectively reduced unwanted, pigmented hair in individuals with skin types IV and V, but was less safe in those with skin type VI.
June 1996 in “Journal of Dermatological Science”
April 2016 in “Journal of The American Academy of Dermatology” Daylight photodynamic therapy is effective and well-tolerated for treating actinic keratoses with minimal side effects.
9 citations
,
November 1999 in “Annals of Plastic Surgery” This study found that ruby laser hair removal causes microscopic epidermal damage but does not lead to cellular hyperproliferation, unlike ultraviolet-irradiated cell damage.
47 citations
,
October 2015 in “Dermatologic surgery” This review discusses the applications of the 308-nm excimer laser in treating various dermatologic conditions and suggests treatment is generally well tolerated, but calls for larger long-term studies.
48 citations
,
June 2000 in “Japanese Journal of Cancer Research” This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.
December 2017 in “Actas Dermo-Sifiliográficas” Scalp cooling reduces chemotherapy-induced hair loss without increasing risk of skin metastases.
January 2026 in “Drug Delivery and Translational Research” This study investigated the integration of crystal engineering and microneedle technology for androgenetic alopecia treatment, finding that microneedles loaded with newly developed Kopexil multicomponent crystals reduced drug diffusion rates in vitro compared to standard formulations.
25 citations
,
March 2019 in “Dermatologic therapy” This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.
4 citations
,
October 2019 in “Skin Appendage Disorders” This case report describes the first known instance of hair and eyebrow hyperpigmentation in a patient after seven months of gefitinib treatment for non-small cell lung cancer.
1 citations
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April 2004 in “Cancer” This study describes that 65% of patients receiving imatinib mesylate in a patient assistance program experienced skin hypopigmentation, primarily in ethnically Chinese individuals, suggesting variability across populations.
November 2022 in “Journal of Investigative Dermatology” This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.
74 citations
,
February 2018 in “Journal of the American Academy of Dermatology” 133 citations
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June 1993 in “Molecular and Cellular Biology” This study found that a truncated region of the K5 promoter directs expression in stratified epithelia, particularly in epidermis, hair follicles, and tongue, potentially involving specific keratinocyte nuclear proteins in regulation.
March 2026 in “Health Science Reports” Among individuals with skin types II and III, this study found the 755 nm laser more effective for axillary hair removal than the dual-wavelength laser, with a better safety profile and enduring results up to 12 months.