research Acid Phosphatase Distribution in the Wool Follicle: Fate of Organelles in Keratinized Cells
Keratinized wool cells still have some organelles like lysosomes and mitochondria.
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research Optical Coherence Tomography-Assisted Diagnosis of Follicular Keratosis of the Chin
OCT can non-invasively diagnose follicular keratosis and other hair follicle disorders.
research RSPO1-Mutated Keratinocytes From Palmoplantar Keratoderma Display Impaired Differentiation and Invasiveness: Implications for Squamous Cell Carcinoma Susceptibility in Patients With 46XX Disorder of Sexual Development
RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
research Advances in Molecular Pathogenesis of Hidradenitis Suppurativa: Dysregulated Keratins and ECM Signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research Single-Cell Transcriptomics Defines Keratinocyte Differentiation in Avian Scutate Scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Wnt/β-Catenin Signaling Stabilizes Hemidesmosomes in Keratinocytes
Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
research Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes
Reducing FOXA2 in skin cells lowers their ability to grow hair.
research Bald Thigh Syndrome in Sighthounds: Revisiting the Cause of a Well-Known Disease
Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice
Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.
research Transcriptome Analysis of Skin from SMP30/GNL Knockout Mice Reveals the Effect of Ascorbic Acid Deficiency on Skin and Hair
Vitamin C deficiency changes gene expression, affecting skin and hair health.
research Phase I/IIa Clinical Trial for Recessive Dystrophic Epidermolysis Bullosa Using Genetically Corrected Autologous Keratinocytes
The gene therapy showed significant wound healing and was safe for treating severe RDEB.
research The Role of the VEGF, KGF, EGF, and TGF-β1 Growth Factors in the Pathogenesis of Telogen Effluvium in Women
Certain growth factors significantly affect hair loss in women with telogen effluvium.
research Differential Expression of KRT83 Regulated by the Transcription Factor CAP1 in Chinese Tan Sheep
CAP1 decreases the expression of a hair-related protein in young Tan sheep's skin.
research A Rare Case of Multiple Keratoacanthomas Treated with Oral Acitretin and Intralesional Methotrexate
A 25-year-old man with multiple skin tumors was successfully treated with acitretin and methotrexate.
research Unusual Eyelid Dermal Keratinous Cysts of Pilosebaceous Origin
Two new types of eyelid cysts were identified, each with different treatment challenges.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Sulfation of Minoxidil in Keratinocytes and Hair Follicles and the Stimulatory Effect of Minoxidil on the Biosynthesis of Glycosaminoglycans
Minoxidil boosts hair growth by undergoing a process in hair follicles and certain skin cells, and by increasing the production of compounds essential for hair growth and maintenance.
research Diffusion Behavior of Poly(Ethylene Imine) Into Keratin Fibers Using Microspectrophotometry
PEI diffuses into hair at a constant rate, and urea speeds up this process.
research Keep Quiet—How Stress Regulates Hair Follicle Stem Cells
Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.
research Nilotinib-Induced Generalized Keratosis Pilaris: Report of a Rare Case
Nilotinib can cause generalized keratosis pilaris.
research Structural Investigation on Damaged Hair Keratin Treated with α,β-Unsaturated Michael Acceptors Used as Repairing Agents
Treatments improved hair surface and scale structure but didn't increase certain bonds in the hair cortex.
research The Main Cause of Hair Rarefaction in Androgenetic Alopecia: Higher Number and Longer Duration of Kenogen Hairs
More kenogen hairs cause hair thinning in androgenetic alopecia, not hair miniaturization.
research Keratosis Follicularis Spinulosa Decalvans: What Syndrome Is This?
Keratosis Follicularis Spinulosa Decalvans is a rare genetic disorder causing skin and hair issues, often inherited through the X chromosome.
research Influence of Urea on the Coloring Ability of a Low-Temperature Coloring Method of Keratin Fibers Using Polyethyleneimine
Urea helps hair dye penetrate better and last longer.
research A Possible Role of Keratinocytes of Skin and Mucous Membranes in Prion Propagation and Transmission
Skin cells might help spread prion diseases like Creutzfeldt-Jakob disease.
research Keratosis Follicularis With Unusual Involvement Of The Scalp
A rare case of severe scalp hair loss and nail issues in keratosis follicularis was observed.
research SCD1 Sustains Homeostasis of Bulge Niche via Maintaining Hemidesmosomes in Basal Keratinocytes
SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.
research High-Performance Wigs via the Langmuir–Blodgett Deposition of Keratin/Graphene Oxide Nanocomposite
New wig coating technique makes them more durable, UV resistant, and less static.
research Application of Kampo Medicines for Treatment of General Fatigue Due to Long COVID
Kampo medicine can help treat general fatigue from long COVID.
research Heat-Killed Enterococcus Faecalis EF-2001 Induces Human Dermal Papilla Cell Proliferation and Hair Regrowth in C57BL/6 Mice
Heat-killed Enterococcus faecalis EF-2001 may promote hair growth and transition hair follicles to the growth phase.