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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

The representation of skin conditions in medical reviews partly matches their real-world impact.

Doctors need to be better prepared to assess and treat obesity in patients.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Patients with PCOS rate their hirsutism higher than clinicians, and these self-ratings are more closely related to their quality of life and risk of depression.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

Premature graying of hair may suggest health issues and currently lacks effective treatments.

Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.

Skin diseases are very common in poor areas, and there's a need for affordable ways to manage and improve skin health.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.

The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

Dental erosion is common in adolescents and is linked to diet and higher socioeconomic status.

Hair treatments cause significant structural changes, especially with excessive heat, regardless of ethnicity.

The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

Family members of North Indian women with PCOS have a high rate of metabolic syndrome.

Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.