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BOOST is a promising, easy-to-use treatment for diabetic foot ulcers that improves healing by reducing inflammation and promoting blood vessel growth.

This study found that 3D imaging may serve as a promising tool for objectively evaluating facial vitiligo repigmentation after treatment with upadacitinib.

This review discusses using extracellular vesicles as less invasive surrogates for assessing drug-metabolizing enzymes and transporters, suggesting potential advancements in precision therapy, but reports no new clinical results.

This study involved formulating an invasome gel loaded with clotrimazole for treating fungal infections and assessed its various properties like spreadability and in vitro drug diffusion.

VYN201 shows promise as a safe and effective treatment for non-segmental vitiligo.

This article reviews autologous cell therapy for facial wrinkles, detailing the use of LaViv and its adverse events, but reports no new clinical results.

Milk-derived vesicles are promising for delivering drugs orally and treating various conditions.

In this study, imiquimod was found to increase regression of cervical intraepithelial neoplasia compared to placebo, though it commonly caused side effects that rarely led to treatment discontinuation.

This review explores the potential roles of extracellular vesicles in various medical fields, emphasizing their promise but noting the need for standardization and clinical testing before widespread application.

This review highlights the potential of drug-loaded extracellular vesicles as a promising drug delivery platform but notes that clinical translation faces challenges due to variability in methods and the need for standardization and safety evaluation.

This study reported that invasomes, utilizing limonene as a component, enhanced the transdermal permeation of finasteride by over 21 times, indicating their potential as a novel drug delivery system.

This review highlights the potential of extracellular vesicle-based therapies for treating various diseases, but it also notes challenges like the lack of regulatory guidelines that hinder their clinical development.

The review found that imiquimod is a promising non-invasive treatment for HPV-related neoplasias, particularly effective for vulvar lesions, but notes that more research is needed to optimize its use.

In this study, topical eflornithine reduced hair regrowth in hirsute patients following intense pulsed light therapy, suggesting it may maintain IPL-induced hair reduction over six months.

This review provides an overview of how advancing imaging technologies, such as tissue clearing and intravital microscopy, are enhancing our understanding of tumor architecture and interactions between cancer cells and the tumor microenvironment, aiding both fundamental cancer research and the development of therapies.

This study introduced a volar skin excisional wound model that closely mirrors human wound healing and supports evaluation of skin regeneration with multiple appendages and innervation.

This study reports that Iressa, an anti-cancer agent, commonly causes acneiform eruptions and xerosis as cutaneous side effects, similar to other agents targeting epidermal growth factor receptors.

This study identified a mutant in Arabidopsis with shorter root hairs due to early growth cessation, implicating the IRE gene in regulating root hair growth duration.

In this study, researchers developed a custom-designed 3D-printed microscope stage insert for inverted confocal microscopes, enhancing the accessibility of long-term intravital imaging of live cell dynamics in live transgenic mice, particularly in the skin.

This industry update reports on various advancements in therapeutic delivery during July 2018, highlighting active mergers, collaborations, and potential developments across fields like gene therapy, immuno-oncology, and rare diseases treatment; however, no new clinical results are presented.

This article discusses the development and clinical progress of PROTAC technology, particularly focusing on the New Drug Application for vepdegestrant, an estrogen receptor-targeting PROTAC, marking significant advancements in targeted protein degradation therapies.

In this study, a novel VDR gene mutation was identified in a child with HVDRR, and the researchers observed that high-dose intravenous calcium therapy led to significant and sustained improvement in rickets symptoms.

This study found that pharmacists using the EVInews database for self-medication information achieved significantly higher quality scores compared to those using other web-based sources.

The study reports that the AVET system showed higher efficiency in transfecting cultured human keratinocytes compared to SuperFect and PrimeFector, with AVET reaching levels of enzyme activity similar to normal cells in keratinocytes from lamellar ichthyosis patients.

The InCISE score is a promising tool for assessing wound healing in head and neck surgery but needs more research for broader use.

This study suggests that the dipeptide Pro-Ile has FGF18-like activity, can penetrate model human epidermis, and may have potential as a cosmetic ingredient for skin and hair regulation.

Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.

In this study, researchers analyzed 355 clinical trials from ClinicalTrials.gov, initiated by the end of 2025, to provide insights into the use of extracellular vesicles as circulating biomarkers or therapeutic interventions, highlighting current research priorities and future trends.

This case study of a neonate with ichthyosis and ILVASC demonstrates how an interdisciplinary approach facilitated a timely genetic diagnosis and management of complications.