December 1963 in “Bulletin of Experimental Biology and Medicine” Radioiodine-131 significantly accumulates in skin and hair.
9 citations
,
January 2024 in “International Journal of Dermatology” Tralokinumab may help improve symptoms of atopic dermatitis and alopecia areata.
13 citations
,
July 1994 in “PubMed” This study found that TPA treatment induced expression of keratins K6 and K16 in mouse epidermis, with K6 expressed across all cell layers and K16 only in post-mitotic cells.
24 citations
,
March 2016 in “Journal of Investigative Dermatology” This study suggests that TIP39 and its receptor PTH2R, identified in human epidermis, may play a role in keratinocyte function and influence skin differentiation.
7 citations
,
January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry”
February 2026 in “Eduvest - Journal Of Universal Studies” This review discusses the molecular mechanisms and therapeutic effectiveness of Janus Kinase Inhibitors for inflammatory skin diseases, suggesting these inhibitors have a rapid onset and favorable safety profile compared to conventional treatments.
January 2025 in “The Egyptian Journal of Hospital Medicine” This study found that keloid patients exhibited significantly higher expression levels of NEDD4-TV3 and IGF-1 genes compared to controls, indicating a potential role of these genes in predicting and understanding keloid formation.
1 citations
,
August 2024 in “JAAD Case Reports” This report presents a rare case of diffuse hair loss resembling alopecia areata, following a tick bite on the scalp.
40 citations
,
September 2010 in “Journal of Biological Chemistry” This study found that keratin K80, structurally similar to hair keratins, is broadly expressed in various epithelial tissues and is involved in intermediate filament formation with multiple type I partners.
6 citations
,
January 2018 in “Multimedia Tools and Applications” This study proposes a method for automatically removing hairs from skin lesion images by using edge-tangent flow for hair detection and texture synthesis for restoring occluded regions with minimal artifacts.
February 2020 in “Definitions” This article discusses the human KRT72 wild-type allele's role in hair formation and reports no new research findings.
October 2025 in “Indian Journal of Dermatology” This study examined the dermoscopic features of five patients with tuberous sclerosis and found that dermoscopy can differentiate characteristic cutaneous features from similar conditions, potentially aiding in earlier diagnosis when other symptoms are subtle or absent.
1 citations
,
July 2025 in “The Open Dermatology Journal” This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.
2 citations
,
January 2020 in “Einstein (São Paulo)” This review discusses the potential of Janus kinase inhibitors as a promising new treatment for alopecia areata, suggesting they could become a first-line therapy in the future, but reports no new clinical results.
December 2023 in “The journal of cell biology/The Journal of cell biology” This study developed the mTurquoise2-Col4a1 mouse model and used fluorescent tagging of collagen IV to offer new insights into basement membrane dynamics during hair follicle budding, revealing that basement membranes are flexible and stable structures in developing skin tissue.
8 citations
,
June 2016 in “Journal of Investigative Dermatology” A rare genetic deletion in the KRT1 gene causes unique skin symptoms in a family.
January 2021 in “Journal of Cancer Therapy” This study described the safety profile of tyrosine kinase inhibitors in treating various solid tumors, finding that the observed toxicities were consistent with existing literature.
139 citations
,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.
30 citations
,
February 2017 in “Histochemistry and Cell Biology” This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.
April 2023 in “Journal of Investigative Dermatology” A new image-based method improves accuracy in measuring hair loss in mice.
August 2024 in “Nihon Ika Daigaku Igakkai Zasshi” In this study, researchers used tissue clearing techniques on human skin and scar tissue for the first time to render them optically transparent, with the aim of revealing atypical structures and improving protocols for observing scar tissue changes.
4 citations
,
January 2025 in “JAAD reviews.” This review discusses how JAK inhibitors, like tofacitinib and baricitinib, show promise in improving conditions like lichen planopilaris and frontal fibrosing alopecia by reducing severity scores and enhancing hair regrowth, though further research on safety and personalized approaches is needed.
38 citations
,
January 2016 in “Cell Death and Disease” This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.
26 citations
,
March 2017 in “Aesthetic plastic surgery” Accidental injection of hyaluronic acid caused temporary hair loss and skin damage, but treatment restored hair and healed the skin.
4 citations
,
March 2025 in “The Journal of Dermatology” This study found that in Asian patients aged 12 and older with alopecia areata and significant hair loss, ritlecitinib showed clinical efficacy in improving hair regrowth and eyebrow and eyelash scores over 48 weeks, with an acceptable safety profile observed throughout.
1 citations
,
January 2025 in “CPT Pharmacometrics & Systems Pharmacology” In this study, the researchers evaluated the exposure-response relationship of ritlecitinib on eyebrow and eyelash regrowth and concluded that the established models justify selecting a 50 mg dose for patients with severe alopecia areata, while highlighting differing efficacy among evaluation methods.
December 2025 in “Actas Dermo-Sifiliográficas” This review analyzes the mechanism and evidence supporting the approved use of ritlecitinib, a JAK3/TEC kinase inhibitor, for treating severe alopecia areata in patients aged 12 and older, highlighting its role in the changing therapeutic landscape of this immune-mediated disease.
17 citations
,
January 1996 in “Aesthetic Plastic Surgery” This study suggests that the tumescent technique effectively provides anesthesia and reduces bleeding during hair micrografting, eliminating the need for multiple needle injections or nerve blocks.
2 citations
,
January 2022 in “International Journal of Medical Sciences” In this study, kartogenin promoted hair growth by enhancing cell proliferation and migration in vitro and extended hair length in mice, suggesting its potential as a treatment for hair loss.