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Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

A20 protein is crucial for normal skin and hair development.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

The representation of skin conditions in medical reviews partly matches their real-world impact.

Advanced human skin models improve drug development and could replace animal testing.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Skin problems are very common in people with end-stage kidney disease.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Mycophenolate mofetil was effective for most patients in treating scarring hair loss, but some had side effects.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.

Antidepressants may improve or resolve scalp dysesthesia in most patients.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Accurate diagnosis and treatment are crucial for managing superficial fungal infections, with terbinafine being the best oral treatment for nail infections.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.

The rise in tinea capitis cases in Stockholm is linked to increased African immigration.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.