research Homeostatic Activation of Epidermal HSD11b1 Affects Skin Innervation and Non-Histaminergic Itch
HSD11b1 affects skin nerves and increases non-histaminergic itch.
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research PSS20 Mediation Modeling and Measurement Characteristics of the Itch Severity Score from a Phase 2B Trial of Oral CP-690-550 in Patients with Moderate-to-Severe Plaque Psoriasis
CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research The Atypical Itch That Rashes: Disseminated And Recurrent Infundibulofolliculitis (DRIF) In An Atopic African American Male
Consider DRIF and perform skin biopsies for persistent papular rashes.
research Pharmacological Evidence for the Involvement of Adenosine Triphosphate Sensitive Potassium Channels in Chloroquine-Induced Itch in Mice
ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.
research Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
research Efficacy of Topical Henna on Itch and Wound Healing in Epidermolysis Bullosa Patients: A Pilot Clinical Trial
Henna ointment may help reduce itching and improve wound healing in patients with epidermolysis bullosa.
research The Effects of Zinc Pyrithione on Dandruff and Itch
Zinc pyrithione in shampoo or rinse reduces dandruff and itching.
research Dovobet Ointment Under Occlusion Overnight for Troublesome Scalp Psoriasis
Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.
research Prioritization of Therapy Uncertainties in Congenital Ichthyosis: Results from a Priority Setting Partnership
The top research priorities for congenital ichthyosis include long-term side effects of oral retinoids, best topical treatments, and treatments for itch and hair loss.
research Lysophosphatidic Acid and Signaling in Sensory Neurons
Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
research Clinical Snippets: Dermatological Studies and Findings
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
research TRP Channels in Skin Biology and Pathophysiology
TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
research Expression of Mu-Opiate Receptor in Human Epidermis and Keratinocytes
μ-opiate receptors in skin cells may affect skin health and healing.
research Generalized Pruritus in Primary Sclerosing Cholangitis: Implications of Histamine Release by Lysophosphatidic Acid
A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.
research Telogen Effluvium With Dysesthesia Has Lower B12 Levels and May Respond to B12 Supplementation
People with TED often have low B12 levels and might benefit from B12 supplements.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Structure and Function of the Skin
The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
research Iron Deficiency Anemia Pruritus: A Review with Proposed Mechanisms of Action
Iron deficiency anemia can cause itching, which often improves with iron supplements.
research Overlaps Between Inflammatory Dermatoses and Ichthyoses: Need for Novel Therapeutic Approaches
Patients with ichthyosis often experience symptoms similar to psoriasis and atopic dermatitis, suggesting that targeted therapies could improve their condition.
research Knismesis: The Aversive Facet of Tickle
Light tickling can be unpleasant and may feel worse for individuals with autism.
research Telogen Effluvium With Dysesthesia Has Lower B12 Levels And May Respond To B12 Supplementation
People with telogen effluvium and scalp discomfort might have low vitamin B12 and could benefit from B12 supplements.
research What Bothers You Most About Your Skin Cancer? 700 Patients Respond
Patients with nonmelanoma skin cancers are most bothered by fear of progression, appearance concerns, and having cancer.
research Is Seborrhoeic Dermatitis Associated with Diffuse, Low-Grade Folliculitis and Progressive Cicatricial Alopecia?
Seborrhoeic dermatitis may cause a condition called "seborrhoeic folliculitis," leading to chronic scalp inflammation and scarring hair loss.
research Lichen Planopilaris Responsive to a Novel Phytoactive Botanical Treatment: A Case Series
A new botanical treatment improved hair growth and symptoms in lichen planopilaris patients.
research Mario Lacouture: How Do I Treat a Patient with Dermatologic Toxicities to EGFR Inhibitors?
Dr. Mario Lacouture recommends preventive and specific treatments for skin side effects caused by EGFR inhibitors to improve patients' quality of life.
research Skin Disease
Skin diseases can greatly affect daily life and require careful treatment and medication review.
research Effect of Nymphaea Caerulea Flower Extract on Improving Scalp Diseases
Nymphaea caerulea flower extract can improve scalp conditions by reducing oil, inflammation, stress hormones, and blood vessel issues.
research Thymic Stromal Lymphopoietin Controls Hair Growth
Thymic stromal lymphopoietin (TSLP) promotes hair growth by stimulating specific skin cells.
research Doctor, My Armpit Hair Has Turned Yellow! Malodorous Yellowish Axillary Hair in an Adolescent Patient
A 15-year-old boy's smelly, yellow armpit hair improved with clindamycin treatment.