May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that natural hair dyes from plant-derived pigments can produce viable colors on gray hair with low irritation potential, though they face challenges in shade range and consistency; some products may also be adulterated, affecting safety perceptions.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review summarizes current research on natural hair dyes, reporting that plant-based formulations can safely provide viable colors on gray hair with minimal irritation compared to synthetic options but face challenges in color range and consistency.
January 2026 in “International Journal of Advanced Research in Science Communication and Technology” This report describes the creation of a natural herbal beard balm formulated to nourish, hydrate, and support healthy beard growth while reducing irritation, using ingredients like coconut oil, rosemary oil, and beeswax.
January 2026 in “Dermatologic Therapy” This study found that a shampoo containing 1% selenium sulfide and 1% salicylic acid significantly improved the clinical signs and symptoms of seborrheic dermatitis and dandruff over an 8-week period.
January 2025 in “International Journal of Pharmaceutical Research and Applications” This study examines the formulation and effectiveness of a natural hair gel made with Mussaenda frondosa leaf extract for its potential anti-dandruff benefits, highlighting its safety and additional advantages for promoting hair and scalp health.
January 2025 in “International Journal of Herbal Medicine” This review highlights that while dandruff affects over 50% of humans and cannot be fully eradicated, it can be controlled through chemical treatments that may cause side effects or herbal remedies such as Neem and Tea tree oil, which have longstanding use in hair care.
May 2024 in “Jurnal Penelitian Farmasi dan Herbal” In this experimental study on rabbits, the authors concluded that a pomade containing 10% meniran leaf extract was an effective hair growth stimulant and could compete with a positive control, fulfilling the required pomade characteristics.
January 2024 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a pure herbal hair oil using fenugreek seeds and aloe vera, reporting that the oil effectively promotes robust hair growth, offers anti-fungal and anti-dandruff properties, and enhances hair glossiness, surpassing the efficacy of existing marketed products.
June 2023 in “Journal of Pharmaceutical and Health Research” In this study with guinea pigs, a hair tonic containing 0.001% caffeine significantly stimulated hair growth, showing higher effectiveness with an average hair length of 18.294 mm compared to a tonic with 0.005% caffeine concentration, which resulted in an average hair length of 16.610 mm.
December 2022 in “Proceeding Bengkulu International Conference on Health” This study concluded that a 5% concentration of celery extract in hair gel provided the best preparation characteristics, including standard parameters for organoleptic properties and spreadability.
December 2021 in “Asian journal of pharmaceutical and clinical research” In this study, researchers formulated a polyherbal hair oil using ingredients like coconut and castor oils, and reported that it boosts hair growth, reduces hair fall and dandruff, and adds shine, with minimal adverse effects compared to market formulations.
This study found that rosemary essential oil can be incorporated into an aromatherapy massage cream, with different oil and water ratios affecting its physical properties.
February 2019 in “Case medical research” The document does not state whether dexpanthenol dermal spray helps skin recover after laser hair removal.
July 1989 in “British Journal of Dermatology” Minoxidil helps increase hair growth and density in people with hair loss, with higher concentrations giving better results.
September 2020 in “Nature, Environment and Pollution Technology/Nature, environment and pollution technology” This study found that Wistar rats fed with grass extracts from mining areas accumulated trace metals, particularly in the spleen, leading to organ pathology and signs of toxicity.
269 citations
,
August 2002 in “Journal of The American Academy of Dermatology” This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.
241 citations
,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the roles of sebaceous gland activity, Malassezia yeast, and individual susceptibility in scalp flaking disorders, including dandruff and seborrheic dermatitis, but reports no new experiment results.
150 citations
,
July 2001 in “Clinics in dermatology” This article discusses hair care practices and hair cosmetics in managing alopecia but reports no new clinical findings; it emphasizes the importance of scalp health and good patient-physician communication.
89 citations
,
March 1990 in “PubMed” This study found that shaving was the most helpful and commonly used temporary hair removal method among women with facial hirsutism.
50 citations
,
November 2015 in “Journal of pharmacological sciences” This study found that applying α-mangostin-loaded nanoparticles significantly improved acne vulgaris in patients, with no notable skin irritation reported in human volunteers.
48 citations
,
January 2002 in “Dermatology” In this study, hair pain (trichodynia) was reported by a significant portion of patients with hair loss, but it did not correlate with the cause or activity of the condition.
43 citations
,
January 2007 in “American Journal of Clinical Dermatology” This study concluded that a combined once-daily solution of 5% minoxidil and 0.01% tretinoin is as effective and safe as the conventional twice-daily 5% minoxidil application for treating androgenetic alopecia in men.
37 citations
,
October 2017 in “Saudi pharmaceutical journal” This study reports that six shampoo brands in Saudi Arabia generally comply with the national specifications, demonstrating good physicochemical properties such as foam stability and pH levels.
35 citations
,
October 2015 in “International Journal of Pharmaceutics” Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
34 citations
,
July 2011 in “International journal of pharmaceutics” This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.
34 citations
,
April 2001 in “PubMed” This study found that eflornithine HCl 13.9% cream reduces unwanted facial hair growth in women, with effects seen in up to 60% of participants over 4-8 weeks, with mostly minor skin irritation reported.
32 citations
,
May 1995 in “Contact Dermatitis” This article reviews previous cases and reports of allergic contact dermatitis from minoxidil but does not provide new clinical findings.
30 citations
,
May 1999 in “Food and chemical toxicology” This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.
30 citations
,
November 1996 in “Archives of Dermatology” This report describes cases of increased hair loss and scalp sunburns in patients using 3% minoxidil and 0.01% tretinoin, suggesting caution with tretinoin use on sunny days.
30 citations
,
April 1990 in “Clinical Pharmacology & Therapeutics” This study found that coadministering minoxidil with tretinoin cream increased minoxidil absorption nearly threefold in healthy males, attributed to increased stratum corneum permeability.