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    Glossary Iron Metabolism

    Iron metabolism refers to the processes by which the body absorbs, utilizes, and regulates iron, an essential mineral crucial for various biological functions, including oxygen transport and DNA synthesis. In the context of hair loss, proper iron metabolism is significant because iron deficiency can lead to anemia, which is often associated with hair thinning and loss. Key distinguishing characteristics of iron metabolism include the roles of ferritin (the storage form of iron), transferrin (the transport protein), and the regulation of iron absorption in the intestines, all of which can impact hair follicle health and growth.

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    1. Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia Blood · 2010 · 245 citations
    2. Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone American Journal of Physiology-Endocrinology and Metabolism · 2014 · 53 citations
    3. Iron Metabolism of the Skin: Recycling versus Release Metabolites · 2023 · 10 citations
    4. Associations Between Iron Metabolism and Obstructive Sleep Apnea Severity in Female and Male Individuals With Self‐Reported Androgenetic Alopecia: A Propensity‐Score Matching Analysis From the EPISONO Database Journal of Sleep Research · 2025
    5. 1173 The Role of Iron Metabolism in Obstructive Sleep Apnea Severity in Individuals with Androgenetic Alopecia (EPISONO) SLEEP · 2025
    6. Differences in male and female pattern hair loss based on androgens, estrogen, iron, vitamin D, lipid metabolism, and genetic regulation Journal of Cutaneous and Aesthetic Surgery · 2026
    7. Variants in Iron Metabolism Genes and Metals Concentrations in Infant Hair Epidemiology · 2008
    8. The iron content of human hair. II. Individuals with disturbed iron metabolism. PubMed · 1956 · 3 citations
    9. Promising applications of red cell distribution width in diagnosis and prognosis of diseases with or without disordered iron metabolism Cell Biology International · 2023 · 17 citations
    10. miR-761-hepcidin/Gpx4 pathway contribute to unexplained liver dysfunction in polycystic ovary syndrome by regulating liver iron overload and ferroptosis Gynecological Endocrinology · 2023 · 16 citations
    11. Stratum-Specific Expression of Human Transferrin Receptor Increases Iron in Mouse Epidermis Journal of Investigative Dermatology · 2006 · 14 citations
    12. The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron. Blood · 2007 · 9 citations
    13. The association between serum ferritin and 25-hydroxyvitamin D and metabolic syndrome in Korean women: the Korea National Health and Nutrition Examination Survey 2010–2012 Journal of Clinical Biochemistry and Nutrition · 2017 · 7 citations
    14. Evaluation of Zinc, Vitamin B12, Folic Acid and Iron Levels and Thyroid Functions in Patients with Chronic Telogen Effluvium Journal of dermatology research and therapy · 2015 · 2 citations
    15. Chronic diffuse hair loss in women: A case-control study with clinical correlation of serum iron profile and thyroid function 2021
    16. Zinc, Copper, and Iron in Selected Skin Diseases International journal of molecular sciences · 2024
    17. THE EFFECT OF REPLENISHMENT OF IRON STORES AFTER PHLEBOTOMY THERAPY IN PORPHYRIA CUTANEA TARDA Acta Medica Scandinavica · 1971 · 63 citations
    18. Why cells need iron: a compendium of iron utilisation Trends in endocrinology and metabolism · 2024
    19. METABOLIC DISOEDEKS AND HAIE GEOWTH British Journal of Dermatology · 1971 · 15 citations
    20. Measurement of Zinc, Copper, Manganese, and Iron Concentrations in Hair of Pituitary Dwarfism Patients Using Flameless Atomic Absorption Spectrophotometry Biological Trace Element Research · 2002 · 7 citations
    21. Role of Iron Deficiency in Chronic Hair Loss Indian journal of forensic medicine and toxicology · 2020
    22. Follow-up of Nutritional and Metabolic Problems After Bariatric Surgery Diabetes Care · 2005 · 240 citations
    23. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis Obesity surgery · 2021 · 19 citations
    24. Major clinical and nutrological findings of the relationship among obesity, metabolic syndrome, and bariatric surgery in the process of hair loss: a systematic review International Journal of Nutrology · 2026
    25. Estimation of Serum Ferritin Level in Female Patients with Telogen Effluvium Hair therapy & transplantation · 2012 · 2 citations
    26. The Protective and Regenerative Potential of Lactoferrin in Hair and Skin Health International Journal of Molecular Sciences · 2026
    27. Unconventional haircare Nature Immunology · 2023
    28. Matriptase-2, A Novel Suppressor of Hepcidin. Blood · 2009
    29. Resident macrophages of the lung and liver: The guardians of our tissues Frontiers in Immunology · 2022 · 4 citations
    30. Demographic findings of patients diagnosed with pernio and comparison of their vitamin B12, folate and ferritin levels with a control group Turkderm · 2019