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research Potassium Channel Openers Increase Aortic Elastic Fiber Formation and Reverse the Genetically Determined Elastin Deficit in the Brown Norway Rat

28 citations, August 2013 in “Hypertension”

Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.

research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies

77 citations, July 2020 in “European Journal of Clinical Pharmacology”

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

research Repurposing of Approved Cardiovascular Drugs

73 citations, September 2016 in “Journal of Translational Medicine”

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

research Drug Repositioning: Current Approaches and Their Implications in the Precision Medicine Era

42 citations, January 2018 in “Expert review of precision medicine and drug development”

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Self-Microemulsifying Systems of Finasteride with Enhanced Oral Bioavailability: Multivariate Statistical Evaluation, Characterization, Spray-Drying and In Vivo Studies in Human Volunteers

research Self-Microemulsifying Systems of Finasteride with Enhanced Oral Bioavailability: Multivariate Statistical Evaluation, Characterization, Spray-Drying and In Vivo Studies in Human Volunteers

39 citations, November 2015 in “Nanomedicine”

Improved Finasteride delivery for hair loss treatment.

research Encapsulation of Finasteride with Native and Modified Gamma-Cyclodextrins: Extensive Characterization of the Complexes

8 citations, July 2020 in “International Journal of Pharmaceutics”

Finasteride's solubility improves with native y-CDs, enhancing hair loss treatment and reducing side effects.

research Impact of Clinical Response on Different Approved Doses in Japan and the United States

4 citations, September 2012 in “Clinical Pharmacology in Drug Development”

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

research Cutaneous Drug Reactions

1 citations, January 2010 in “Elsevier eBooks”

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

research DPP-4 Inhibition with Linagliptin Ameliorates the Progression of Premature Aging in Klotho−/− Mice

20 citations, December 2017 in “Cardiovascular diabetology”

Linagliptin slows down premature aging in certain mice.

research Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges

2 citations, May 2023 in “Nanomaterials”

Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.