research Rapid High-Performance Liquid Chromatographic Method for Detection of Interindividual Differences in Carcinogen Metabolism
Human hair follicles can assess carcinogen metabolism and imidazole compounds might be effective anticarcinogens.
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research Can We Halt Male Androgenetic Alopecia Progression Without Antiandrogenic Drugs?
Only anti-androgenic drugs likely halt AGA progression.
research Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss
FPHL affects hair density and diameter, causing visible hair loss in older women.
research Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse
A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
research Electrophoretic Variability in Human Head Hair: Polyacrylamide Gel Electrophoresis of Hair Proteins in the Presence of Sodium Dodecyl Sulfate and Urea
Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.
research Topical Formulations Containing Finasteride: Determination of Finasteride Penetration into Hair Follicles Using the Differential Stripping Technique
Formulation P-08-016 better targets hair follicles for baldness treatment.
research Platelet-Rich Plasma in Androgenetic Alopecia
PRP can help treat hair loss but needs standardized methods for best results.
research Culturing of Melanocytes from the Equine Hair Follicle Outer Root Sheath
Researchers successfully grew horse skin cells that produce pigment from hair follicle samples.
research Melatonin Increases Anagen Hair Rate in Women With Androgenetic Alopecia or Diffuse Alopecia: Results of a Pilot Randomized Controlled Trial
Melatonin helps hair growth in women with hair loss.
research Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels
Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.
research Reflections on How Wound Healing-Promoting Effects of the Hair Follicle Can Be Translated into Clinical Practice
Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
research Androgen Levels and Semen Parameters Among Former Users of Finasteride With Persistent Sexual Adverse Effects
research Estimation Methods for Human Circadian Phase Using Peripheral Tissues
New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.
research Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist
CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
research The Difficulty of Finding Healthy Volunteers
Most people who volunteered for a health study had medical issues, showing the need for careful screening before trials.
research Longitudinal Association Between Saliva and Hair Cortisol Concentration: A Systematic Comparison
Hair cortisol is a reliable marker of long-term cortisol levels and is linked to daytime saliva cortisol but not morning levels.
research Hair Glucocorticoid Levels in Parkinson’s Disease
People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.
research Cyclosporine-Induced Alopecia: A Case Report, FDA Adverse Event Reporting System Analysis and Literature Assessment
Cyclosporine may cause hair loss, so patients need monitoring.
research Melasma, A Photoaging Disorder
Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
research The Therapeutic Response of Platelet-Rich Plasma for Androgenetic Alopecia Showed No Correlation with Growth Factors and Platelet Number
PRP treatment can increase hair growth in male pattern baldness, but this effect is not linked to the levels of growth factors or the number of platelets.
research Recent Progress of Polymeric Microneedle-Assisted Long-Acting Transdermal Drug Delivery
Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.
research Incorporation of Isotopically Labeled Cocaine and Metabolites into Human Hair: Dose-Response Relationships
Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.
research The Role of Hair Follicles in the Percutaneous Absorption of Caffeine
Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
research Genome-Wide Association Study Identifies a New Locus JMJD1C at 10q21 That May Influence Serum Androgen Levels in Men
A new gene, JMJD1C, may affect testosterone levels in men.
research Absorption Sites of Orally Administered Drugs in the Small Intestine
Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.
research Morphometric Analysis of the Human Scalp Hair Follicle: Practical Implications for the Hair Transplant Surgeon and Hair Regeneration Studies
The research provides specific measurements for hair follicles that can improve hair transplant and regeneration techniques.
research Sulphation Catalyzed by the Human Cytosolic Sulphotransferases: Chemical Defense or Molecular Terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Female Pattern Hair Loss, Sebum Excretion, and the End-Organ Response to Androgens
Hair loss in women not always linked to increased oil production; other factors may be involved.
research Hepatotoxicity with Low- and Ultralow-Dose Flutamide: A Surveillance Study on 203 Hyperandrogenic Young Females
Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.
research Production Rates of Testosterone and Dihydrotestosterone in Female Pattern Hair Loss
Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.