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Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Citrullus colocynthis has pain-relieving, anti-inflammatory, antidiabetic, and hair growth benefits, but can cause side effects like colic and diarrhea.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Melatonin may reduce skin damage caused by X-rays in rats.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

A gene called HDAC9 might be a new factor in male-pattern baldness.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Insulin resistance linked to obesity may increase COVID-19 severity.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.