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Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Cronkhite-Canada syndrome can cause multiple gastrointestinal polyps and various physical symptoms.

Hair chemicals don't cause SLE but may increase skin issues in those with SLE.

An imbalanced gut and lack of biotin can cause hair loss in mice.

People with alopecia areata often have lower vitamin D levels than healthy people.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.

Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Intestinal stem cells can help repair skin damage from radiation.

Older men with late-onset lupus have a higher mortality rate than women.

Skin issues can indicate immune system problems.

Satoyoshi syndrome is likely an autoimmune disease that mainly affects young women and improves with immune-related treatments.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Polymeric nanoparticles show promise for treating skin diseases.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Oral steroids may effectively treat recurrent intussusception in children with ILH, possibly avoiding surgery.

Systemic diseases can cause hair loss, which is often reversible with treatment.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.