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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Androgens can both increase and decrease hair growth in different parts of the body.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Sulforaphane from broccoli can help protect skin from sun damage.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Stem cell self-renewal is complex and needs more research for full understanding.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Finasteride may cause long-lasting sexual side effects.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.