47 citations,
November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
47 citations,
April 2012 in “The Plant Journal” Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.
46 citations,
March 2019 in “Journal of Pineal Research” Melatonin improves cashmere goat hair growth and quality by increasing antioxidants and reducing cell death.
26 citations,
October 2016 in “Biomolecules & Therapeutics” 3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
25 citations,
February 2019 in “Genomics” Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
25 citations,
November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
24 citations,
April 2017 in “Oncology Reports” The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.
22 citations,
February 2008 in “Journal of Dermatological Science” EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.
18 citations,
September 2018 in “Experimental physiology” Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
18 citations,
February 2018 in “International Journal of Molecular Sciences” PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
18 citations,
April 2011 in “International Journal of Molecular Medicine” Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
17 citations,
June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Hair in mammals likely evolved from glandular structures, not scales.
16 citations,
December 2018 in “Plant Science” Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.
11 citations,
July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
10 citations,
May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
8 citations,
February 2016 in “The American Journal of Dermatopathology” Hair transplants can make hair follicles larger and hair shafts thicker.
7 citations,
December 2015 in “Experimental Dermatology” Sh-Polypeptide 9 may be better than minoxidil for hair growth and protection against damage.
6 citations,
April 2022 in “Frontiers in cell and developmental biology” The research identified key proteins and genes that may influence wool bending in goats.
6 citations,
January 2017 in “Journal of toxicologic pathology” Rabbit skin with active hair growth shows thicker, redder areas due to larger, more numerous hair follicles and increased blood vessels.
6 citations,
April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
4 citations,
December 2020 in “Mammalian genome” Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
4 citations,
September 2020 in “Andrologia” Oregano extract helps fix testis and sperm damage caused by finasteride.
November 2024 in “Research Square (Research Square)” Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.
October 2023 in “Frontiers in endocrinology” Effective PCOS treatments require targeting specific signaling pathways.
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
260 citations,
June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
211 citations,
March 2011 in “Journal of Lipid Research” A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.
March 2024 in “EMBO molecular medicine” Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.