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The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Hair loss can be caused by stress, infections, drugs, and various diseases, with treatment depending on accurate diagnosis.

The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.

Shrinking of oil glands in the skin is a key sign of hair loss linked to TNF inhibitor drugs and may improve if the treatment is stopped.

New treatments for hair loss show promise but need more research to confirm safety and effectiveness.

Recognizing skin symptoms in children can help diagnose and manage serious diseases early.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

A dietary supplement with Boswellia serrata, Curcuma longa, and Vitis vinifera showed potential improvement in hair health for telogen effluvium patients, but more research is needed.

Some cases of tinea capitis, a fungal scalp infection, can look like scarring hair loss due to the body's immune response and the fungus itself.

Naproxen is not the cause of hair loss in a child; it's due to a toxic event with expected hair regrowth.

Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.

A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.

Early treatment of acne is crucial to prevent scarring and psychological effects.

Low ferritin levels can indicate iron deficiency as a cause of hair loss.

Getting insurance to cover the hair loss treatment tofacitinib is hard because it's not officially approved for that use.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Generalized vitiligo in Chinese patients is linked to other autoimmune diseases, especially in familial cases.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.