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The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Polymeric nanoparticles show promise for treating skin diseases.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

New nanocomposites with copper show promise for healing burn wounds and regenerating skin.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

HFMs can help study hair growth and test potential hair growth drugs.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Shampoos are designed to clean and improve hair and scalp health, with specific ingredients for different hair types and conditions.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.