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Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

New treatments for male hypogonadism are effective and should be personalized.

Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

Fat cells are important for tissue repair and stem cell support in various body parts.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Lower vaspin levels in the blood may indicate a better response to fertility treatment in women with PCOS.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.