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The document concludes that proper diagnosis and tailored long-term treatment can effectively manage androgenic disorders in women, improving patient care outcomes.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Aging men face unique health issues like erectile dysfunction, prostate problems, and baldness.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Testosterone's role in women's sex drive is unclear and needs more research, as low levels don't always mean less sexual interest and high levels can cause side effects.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Excess androgens may cause PCOS, not just be a symptom.

Effective PCOS treatments require targeting specific signaling pathways.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

A girl with red hair developed hair-pulling and body image disorders after being bullied for her hair color.

Women with moderate body hair have higher levels of certain hormones and may benefit from treatment that increases sex hormone-binding protein.

Niacinamide does not promote hair growth.

High BMI worsens hair growth in women with PCOS.

Men are increasingly removing body hair for looks and cleanliness, and while hair loss can cause distress, it doesn't affect their self-esteem as much as it does in women.

Prostaglandin analogs like Latanoprost might help grow hair on the scalp and body.

Acne severity in women may not be linked to increased male hormone indicators like excess body hair, menstrual irregularities, or hair loss.

Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.

The document explains hair growth, hair loss types, and other hair-related terms.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Hair transplantation surgery has improved, becoming more popular and efficient, but patient dissatisfaction remains due to unrealistic expectations.

Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.

Hair transplantation techniques have improved over 12 years, with follicular unit grafting providing more natural results and potential future advances in automation and genetics.

People with denser forearm hair have a higher risk of certain skin cancers.

Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.

Oral minoxidil may slow male pattern baldness and cause body hair growth, but hair loss can happen after stopping it.

Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.