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450-480 / 1000+ resultsresearch The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches
In mouse models, this study showed that transplanted dermal papilla and dermal sheath cells can integrate into hair follicles, promoting hair growth and extended anagen phases, with their effectiveness influenced by factors such as immune response and cell passage number.
research Detection of human papillomavirus type 56 DNA, belonging to a mucous high-risk group, in hair follicles in the genital area of a woman no longer suffering from viral warts
This study suggests that hair follicles in the genital area may serve as reservoirs for high-risk human papillomaviruses.
research ILK modulates epithelial polarity and matrix formation in hair follicles
This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.
research LB890 Cyclic hair growth requires spatiotemporal heterogeneity in hair follicle signaling network
This study found that a mathematical model predicts signaling heterogeneity in epithelial outer root sheath cells is necessary for hair follicles to maintain size and grow long hair fibers, supported by molecular experiments.
research Skin fibroblast functional heterogeneity in health and disease
In this source, recent single-cell RNA-sequencing advances reveal significant transcriptional heterogeneity among skin fibroblasts, and the discussion focuses on the distinct subtypes' roles in skin homeostasis, repair, and their evolution in fibrotic diseases like keloid scars and cancer.
research Insulin Resistance in Patients with Androgenic Alpoecia”
In this study, patients with androgenic alopecia were found to have higher levels of insulin, glucose, and HOMA-IR compared to healthy individuals, suggesting distinct metabolic profiles that may contribute to the condition's development.
research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.
research Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice
This study revealed that heterozygous mice with the hairy ear mutation exhibited significant gene expression changes related to hair growth, such as upregulation of hair keratin and keratin-associated proteins, shedding light on the Hoxc gene cluster's role in this phenotype.
research Assistants’ Corner
This piece discusses preparations and networking opportunities for the ISHRS 8th Annual Meeting, but it presents no new research findings.
research 0955 Selective BET inhibition as potential hidradenitis suppurativa treatment
research A modified Sobel filter-based automated numerical algorithm enables immediate trichoscopic assessment of hair diameter diversity in male and female pattern hair loss
A new computer tool quickly measures hair thickness differences in people with common types of hair loss.
research ISID0652 – Efficacy comparison of photobiomodulation devices in the treatment of androgenetic alopecia
This study found that in-person photobiomodulation treatments improved hair growth in men and some women with androgenetic alopecia, except for the laser band and combination laser/LED helmet in women.
research Hairless Plays a Role in Formation of Inner Root Sheath via Regulation of Dlx3 Gene
In this study, researchers found that overexpression of the hairless protein in Hr mutant mice disrupts inner root sheath formation by downregulating Dlx3 and associated keratins in hair follicle development.
research hKAP1.6 and hKAP1.7, Two Novel Human High Sulfur Keratin-Associated Proteins are Expressed in the Hair Follicle Cortex
In this study, researchers identified two new keratin-associated proteins, hKAP1.6 and hKAP1.7, in human hair follicles, contributing to understanding hair fiber differentiation.
research Pure Hair‐Nail Ectodermal Dysplasia: Expanding the HOXC13 Genotypic Spectrum
research [A three-dimensional observation of human hair tissue treated by modified trypsin-HC1 method].
This study reported detailed three-dimensional ultrastructural observations of human hair and hair follicles using a modified preparation method, including morphological differences in hair bulb cell layers and surface projections on root sheath cells.
research Hereditary 1,25-dihydroxyvitamin D-resistant rickets (HVDRR): clinical heterogeneity and long-term efficacious management of eight patients from four unrelated Arab families with a loss of function VDR mutation
In this study, eight patients with hereditary vitamin D-resistant rickets who share a specific VDR mutation showed improved clinical symptoms except alopecia after up to 11 years of treatment.
research Trichohyalin: A structural protein of hair, tongue, nail, and epidermis
research Two siblings with uncombable hair syndrome: A new pathogenic variant
This case report described two siblings with uncombable hair syndrome characterized by unique hair features, and identified a new pathogenic variant in the PADI3 gene (c.1374dup; p. Val459ArgfsTer15) not previously documented.
research Bidirectional binding property of high glycine–tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair
This study suggests that the mechanical robustness of hair may be enhanced by the binding interactions of keratin-associated proteins, particularly KAP8.1, with intermediate filament proteins.
research HIV Symptom Clusters are Similar Using the Dimensions of Symptom Occurrence and Distress
In this study, symptom clusters in people living with HIV were relatively consistent across different symptom experiences and may help develop targeted interventions for managing multiple symptoms simultaneously.
research Computational derivation of a molecular framework for hair follicle biology from disease genes
This study compiled an archive of 684 genes associated with monogenic hair disorders, identifying previously unrecognized components of Hippo signaling and proposing a new biologically-grounded disease taxonomy.
research Genetic Polymorphisms of the 3'-Untranslated Regions (3'-UTR) of the HSP 70 Gene in Moa Buffalo (Bubalus bubalis)
In this study, researchers identified two significant genetic polymorphisms in the 3'-UTR of the HSP70 gene in Moa buffalo, which may play an important role in heat adaptation, providing insights for conservation and performance improvement in tropical climates.
research Human hair follicle organ culture: theory, application and perspectives
This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.
research Analisis IMT Terhadap Alopesia Androgenik Fakultas Kedokteran, RS Ibnu Sina Dan Menara UMI Makassar
This study observed an association between body mass index and androgenetic alopecia, with the highest prevalence occurring in individuals with a normal BMI at 34.8%.
research 026 Altered Skin Wound Healing in Homeobox Gene Msx-2 Knockout Mice
In this study, Msx-2 knockout mice showed enhanced re-epithelialization and faster wound closure compared to wild-type controls, suggesting Msx-2 may influence skin morphogenesis during wound repair.
research A mechanical-assisted post-bioprinting strategy for challenging bone defects repair
This study demonstrated that a mechanical-assisted post-bioprinting strategy significantly increased cell numbers and enhanced regenerative capabilities in hollow hydrogel-based scaffolds for bone defect repair in vivo.
research Home‐based diphenylcyclopropenone immunotherapy for alopecia areata: A large retrospective study of 94 cases
This abstract provides supplementary materials and directs queries to the corresponding author but presents no new research findings.
research Presentation1_BBS7–SHH Signaling Activity Regulates Primary Cilia for Periodontal Homeostasis.pdf
This study found that BBS7 downregulation in occlusal hypofunctional periodontal ligament tissue is associated with reduced Sonic hedgehog signaling activity, potentially playing a key role in maintaining PDL homeostasis.