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This case report describes a 7-year-old child with linear lupus panniculitis of the scalp, treated successfully with a combination of hydroxychloroquine, topical and intralesional steroids, and a topical calcineurin inhibitor.

Low-intensity ultrasound may help protect hair follicles from chemotherapy-induced hair loss.

In this observational study, dermoscopy was found to be a useful tool in diagnosing lichen planopilaris among patients with primary cicatricial alopecia.

This study found that targeting CISD1 with the compound NL-1 reduced mitochondrial dysfunction and reactive oxygen species accumulation, protecting against cisplatin-induced hearing loss in cell models and mice, without affecting cisplatin's cancer-fighting effectiveness.

In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.

In this study, a computer-aided imaging system accurately measured the width of balding areas in female pattern hair loss, correlating strongly with clinical staging severity.

This study found that the oral IRAK4-inhibitors BAY 1834845 and BAY 1830839 reduced skin inflammation and systemic inflammatory responses in healthy volunteers, showing similar pharmacodynamic effects to prednisolone when challenged with topical imiquimod and intravenous LPS.

This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.

The authors report that a 62-year-old woman with invasive conjunctival squamous cell carcinoma experienced complete remission two years after combining cemiplimab, retinoic acid, and IFNα-2b treatments, highlighting potential utility despite limited availability of IFNα-2b.

A man's skin cancer improved and some of his hair grew back after treatment with a special light therapy and a medication.

This retrospective study found that applying local skin precooling before scalp nerve block significantly reduced injection site pain during PRP mesotherapy for patients with androgenetic alopecia, compared to those who did not receive precooling, thus improving patient comfort and compliance.

This study found that expert consensus endorsed myo-inositol, alone or combined with folic acid and vitamin D₃, as an effective, well-tolerated option for managing acne and hirsutism in PCOS.

This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.

This retrospective cross-section study found that in a cohort of Pica patients in Iraq, 92.4% were female, and many had low levels of ferritin, hemoglobin, and vitamin D, which may contribute to the disorder by causing psychological issues.

Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.

This study concluded that intramuscular administration of medium-dose cyproterone acetate with oral ethinylestradiol is highly effective in managing hirsutism, showing better response rates than high-dose oral treatment.

This study reports that while DCP had similar treatment efficacy in propylene glycol and isopropanol for alopecia areata, the formulation in isopropanol was better tolerated.

The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.

In this study, the researchers reported that NMMHC IIA dissociates from PAR1 and activates the CREB3/ARF4 pathway, worsening thrombin-induced blood-brain barrier damage, suggesting it as a potential therapeutic target for blood-brain barrier-related diseases.

This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.

In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.

In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.

This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.

This article describes Amy Senior's evolving views on the Joint Council for Cosmetic Practitioners and reports no new research findings.

This study highlights that variations in clinical outcome reporting can undermine the validation of NTCP models for RIA, stressing the need for a standardized and objective scoring system.

This study suggests that IL-1β produced by dermal papilla cells, regulated by protein kinase C, may inhibit human hair follicle growth through paracrine signaling.

The research observed that a penguin cap scalp cooling system may effectively reduce chemotherapy-induced alopecia, though its success varies due to individual characteristics and treatment regimens.

This study concluded that monthly pulse IV cyclophosphamide is effective for severe lupus nephritis in Indian patients, achieving complete or partial remission in 68.9% of cases, though longer follow-up is needed.

This review examines the pathophysiology of PCOS and reports that myoinositol may improve menstrual regularity, insulin sensitivity, and reproductive outcomes, with comparable efficacy to metformin and often better tolerability.